Expanding the frontiers of gene editing: the role of genotypic confirmation

Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop treatments to help improve the human condition. These critical insights, however, hinge on the precision of genome engineering. Thus, confirmation of genetic alterations during the gene editing process is important to the successful interpretation of experiment results and the safety and efficacies of downstream therapies.

In this webinar, Dr. Stephen Jackson, applications senior manager at Thermo Fisher Scientific, discusses the utility of these genomic tools in modeling diseases, plants and animals, as well as the importance of genotypic confirmation of gene edits.

Key topics include:

• Review case studies on the latest genomic tools in modeling diseases, plants, and animal models
• Discuss the benefits of genomic confirmation
• Identify key applications of targeted sequence interrogation for gRNA optimization, primary pool analysis, secondary single clone screening & final verification of engineered cells & animal models
• Uncover the benefits of the capillary electrophoresis-based genetic analyzers in accelerating scientific discoveries and novel gene editing-based therapies