Human Breast Organoid Models for Cancer Research

Breast cancer is the most common type of cancer and the leading cause of cancer deaths for women. Despite considerable ongoing research efforts focused on increasing our understanding breast cancer tumorigenesis and progression, the factors that regulate human breast cancer development at the cellular and molecular level remain poorly understood. And there is a growing need for immune-competent human breast ex vivo models that recapitulate the native breast tissue microenvironment to help elucidate the underlying mechanisms of breast cancer risk factors. In this webinar, Dr. Xiaojiang Cui of Cedars-Sinai Medical Center will provide an overview of the most recent advances in 3D organoid models derived from induced pluripotent stem cells (iPSCs) and patient-specific breast tissue. He’ll discuss how his lab:

 

 

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