Director of Business Development at NuProbe
BIOGRAPHY
FEB 09, 2022 9:00 AM PST
An Approach to Ultrasensitive Detection and Quantification of Copy Number Variations (CNVs) and Mutations
Speakers
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Jinny Zhang, Ph.D.
Associate Director of Innovation at NuProbeBIOGRAPHY
Event Date & Time
Date: February 09, 2022
Time: 09:00am (PST), 12:00pm (EST)
Abstract
In this webinar we will introduce Quantitative Amplicon Sequencing (QASeq): a highly sensitive and robust NGS-based method for the detection and quantification of low frequency Copy Number Variations (CNVs) and Single Nucleotide Variants (SNVs) in a wide range of sample types including fresh frozen, FFPE, and cell-free DNA. We will demonstrate that QASeq can accurately detect CNVs down to 5% heterozygous single copy gain or loss (ploidy=2.05/1.95). Additionally, we will introduce NuProbe’s custom assay development program.
Learning Objectives
By the end of the webinar, the attendees will be able to:
- Identify main challenges of current methods (IHC, FISH, NGS, and PCR) for sensitive CNV calling and learn how NuProbe’s ultrasensitive QASeq NGS technology for tissue and liquid biopsy applications can overcome these challenges.
- Review NuProbe's proprietary QASeq technology to increase sensitivity and describe the construction and validation of NuProbe’s custom assays.
- Illustrate the process of developing and validating QASeq NGS panels for the simultaneous for the simultaneous and ultrasensitive detection of CNVs and mutations in the ERBB2 gene as well as other target genes.
- Provide an overview of custom assay development and validation for biopharma and research applications.
Disclaimer: Products are for research use only, not for use in diagnostic procedures.
Webinars will be available for unlimited on-demand viewing after live event.
LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.
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