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JUN 05, 2024 11:40 AM PDT

Genotyping platforms for discovery, quality control and genomic breeding

SPONSORED BY: LGC Biosearch Technologies

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The need for sustainable agricultural practices has become more crucial than ever, as farmers seek innovative solutions that benefit their livelihoods and contribute to environmental improvement. CoverCress Inc. (CCI) embraced the challenge of developing a new rotational cash crop that addresses multiple issues simultaneously; the creation of a crop that is a sustainable feedstock source for producing low greenhouse gas emitting, renewable fuels, sequesters carbon, improves soil quality and provides the right incentives to farmers.

Following the creation of CoverCress^®, a domesticated form of Thalaspiarvense, it was vital for efficient genotyping to be performed to ensure the ongoing success of the product. This case study outlines how CCI utilised a high-throughput targeted genotyping platform to integrate legacy data and develop novel genotyping markers. The implementation of Flex-Seq by CCI has enabled genetic mapping of very complex traits to inform current and future genomic selection programmes to improve quality of the germplasm.

Read time: 5 minutes

Pages: 5

About the Sponsor

LGC Biosearch Technologies

Biosearch Technologies is the comprehensive genomics portfolio from LGC, providing products and services for genomic analysis that support mission critical applications for global customers in agrigenomics and human healthcare.

The portfolio offers integrated tools and technologies to accelerate sample preparation, amplification, cloning and expression, next generation sequencing (NGS), custom oligonucleotide synthesis, nucleic acid chemistry reagents, and oligo therapeutics.

Whether through sbeadex™ DNA purification, oligos and reagents (KASP™, BHQplus™ Probes, BHQ™ Probe Master Mix), or proprietary sample prep and PCR instrumentation (oKtopure™, SNPline™, Nexar™ and IntelliQube™), we enable our customers from discovery to production-scale testing.

Biosearch Technologies is a leader in the agricultural genomics market and is increasingly adopted by researchers, with over 2,000 scientific papers citing KASP assays. Key applications include validation and screening of newly discovered SNPs in Marker-Assisted Selection and Marker-Assisted Breeding programmes for both plants and livestock.

Globally, our cGMP manufacturing and ISO 13485-compliant facilities support supply chain continuity, complementing our customers' product development pipelines through our robust research grade and cGMP oligonucleotide manufacturing that achieves consistent scale up. For molecular diagnostics, Biosearch Technologies has proven expertise in NGS, isothermal, qPCR-based applications where our tools and technologies such as BHQ probes and proprietary PCR platforms are frequently used in LDTs, ASRs and in vitro diagnostics. Through our recently acquired Lucigen portfolio, we also offer custom and bulk enzymes and buffers as critical components for molecular diagnostics.

Sales offices are located in China, Germany, Singapore, UK, and US. Sales representatives are available throughout Europe, Latin America, and Asia Pacific, with distributors in other key territories. Visit www.biosearchtech.com