Follow
Whole Genome Sequencing
Whole Genome Sequencing: is the process of determining the complete DNA sequence of an organism's genome. In order to do so, you must entail all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast.
NOV 12, 2015 | 9:00 AM
Introduction and adoption of whole-genome sequencing has enabled new methods of investigation in the quest for answers in diagnostic odyssey cases as well as in the broader study of genetic d...
SEP 30, 2015 | 1:30 PM
Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...
SEP 30, 2015 | 6:00 AM
The genome determines changes of the transcription profile upon environmental changes and finally determines how a cell reacts. A comparative genome and transcriptome analysis of the same sam...
SEP 15, 2015 | 8:00 AM
Chromosomal microarray analysis (CMA) is an established technology, which has demonstrated great sensitivity and specificity for detecting genome-wide copy number variants (CNVs). CMA represe...
MAY 14, 2015 | 7:30 AM
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
MAY 13, 2015 | 3:00 PM
Long noncoding RNAs (lncRNAs) are increasingly recognized as having key regulatory roles in development and disease. However, these regulatory molecules often have short half lives and are ex...
MAY 13, 2015 | 10:30 AM
Advanced sequencing technologies have made population scale whole genome sequencing a possibility. However, current strategies for analysis of this data rely upon parallelization approaches t...
JAN 27, 2015 | 2:00 AM
Formalin Fixed, Paraffin Embedded (FFPE) tissues are rapidly being adopted for transcriptome analysis in conjunction with targeted and whole genome sequencing. Harsh formaldehyde fixation an...
OCT 30, 2014 | 9:00 AM
Both cell free DNA (cfDNA) and circulating tumor cells (CTC) represent important possible templates for mutation analysis of clinical samples. Each template has different theoretical advantag...
