The new animal facility is designed to breed and house rodents with the best quality of macro and micro environment and house the maximum possible number of rodents per sf2. This new facilit...
The 2011 Guide for the Care and Use of Laboratory Animals has required that institutions place importance on assuring that staff working with animals are trained and competent to perform thei...
Education and training is closely linked to the quality of performance of all levels of LAS personnel and directly effects both the welfare of the animals used in research and the quality of...
The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
Regulations and guidelines governing the use of animals in research require minimization of pain and distress. However, pharmacologic treatments to prevent or alleviate pain can interfere wit...
The title of this presentation could have been Training within laboratory animal science - where we are and where we should be. While training has been the domain of facility managers for ma...
It is increasingly recognized that the genetic background (i.e., all genomic sequences other than the gene(s) of interest) can have profound influences on the phenotype of an animal model. I...
Nonhuman primates in captivity are typically provided with a multitude of behavioral management opportunities, including naturalistic social groupings, foraging devices, complex physical envi...
Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
It is commonly recognized that technicians are the backbone of a successful animal research program. Unfortunately, the invisible contributions that they make as well as the valuable high lev...
All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
Environmental enrichment can be defined as altering the living environment of captive animals in order to provide opportunities to express more of their natural behavioral repertoire. The cha...
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
Although genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with cancer, the contribution to risk of these variants is small, rende...
Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
Prostate cancer epithelial cells depend on androgens for their survival. Because of this dependence, androgen deprivation therapy is the major treatment of advanced prostate cancer. Such ther...
Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
Recent data have confirmed the ability of cardiac troponin (cTn) measurements to identify those who are developing cardiotoxicity in response to potentially cardiotoxic chemotherapeutic agen...
The eukaryotic translation initiation factor eIF4E is a potent oncogene estimated to be elevated in about 30% of human cancers including cancers of the breast, prostate, lung, colon as well a...
The new animal facility is designed to breed and house rodents with the best quality of macro and micro environment and house the maximum possible number of rodents per sf2. This new facilit...
The 2011 Guide for the Care and Use of Laboratory Animals has required that institutions place importance on assuring that staff working with animals are trained and competent to perform thei...
Education and training is closely linked to the quality of performance of all levels of LAS personnel and directly effects both the welfare of the animals used in research and the quality of...
The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
Regulations and guidelines governing the use of animals in research require minimization of pain and distress. However, pharmacologic treatments to prevent or alleviate pain can interfere wit...
The title of this presentation could have been Training within laboratory animal science - where we are and where we should be. While training has been the domain of facility managers for ma...
It is increasingly recognized that the genetic background (i.e., all genomic sequences other than the gene(s) of interest) can have profound influences on the phenotype of an animal model. I...
Nonhuman primates in captivity are typically provided with a multitude of behavioral management opportunities, including naturalistic social groupings, foraging devices, complex physical envi...
Modern biomedical research greatly benefits from sophisticated techniques which can detect even the most subtle alterations between different individuals or groups. This has raised the bar fo...
It is commonly recognized that technicians are the backbone of a successful animal research program. Unfortunately, the invisible contributions that they make as well as the valuable high lev...
All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
Environmental enrichment can be defined as altering the living environment of captive animals in order to provide opportunities to express more of their natural behavioral repertoire. The cha...
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
The NCI's Therapeutically Applicable Research to Generate Effective Treatments (TARGET) is a comprehensive genomic characterization initiative to determine the molecular changes that drive th...
Although genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) associated with cancer, the contribution to risk of these variants is small, rende...
Personalized medicine is transforming biomedical research and healthcare service delivery. Disease definition, diagnosis, treatment, and prevention are being fundamentally altered by the capa...
Prostate cancer epithelial cells depend on androgens for their survival. Because of this dependence, androgen deprivation therapy is the major treatment of advanced prostate cancer. Such ther...
Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
Many drugs currently used for anti-cancer therapy demonstrate significant inter-individual variability that cannot be normalized using body weight or body surface area. There is an increasing...
Recent data have confirmed the ability of cardiac troponin (cTn) measurements to identify those who are developing cardiotoxicity in response to potentially cardiotoxic chemotherapeutic agen...
The eukaryotic translation initiation factor eIF4E is a potent oncogene estimated to be elevated in about 30% of human cancers including cancers of the breast, prostate, lung, colon as well a...