Tumors and the immune response interact in various ways. Tumors try to suppress the immune response in an effort to promote their growth and survival. The anti-tumor immune response, on the other hand, identifies tumor cells and kills them. Both tumors and the immune response elicit various mechanisms to combat the actions of the other.
There has been a great deal of renewed attention in immuno-oncology over the last decade. Therapies for cancer are being developed, approved, and administered that can either initiate,...
Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. Recent studies show that response to checkpoint blockade does not...
DATE: September 7, 2017TIME: 9:00AM PT, 12:00PM ETThe success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on can...
This seminar will give attendees a full overview of two new Miltenyi cell sorting platforms, the MultiMACS X and the CliniMACS Prodigy and how these instruments can be used in various primary...
DATE: May 2, 2017TIME: 8:00am PT, 11:00am ET, 4:00pm GMT, 5:00pm CETThe natural immune responses that patients develop to their own tumors, as well as therapeutic regimens employin...
DATE: April 25, 2017TIME: 10:00am PT, 1:00pm ETImmunotherapy has emerged as one of the most promising options for the future treatment of a growing number of cancers and is to...
DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance. This adaptive immunity can be reversed to stimulate the endogenous immune re...
New generations of treatments successfully target cancer cell signaling and modulate anti-cancer immunity to improve outcomes for advanced-stage malignancies. Such clinical responses are gove...
The immune system is capable of recognizing tumors and eliminates many early malignant cells. However, tumors evolve to evade immune attack, and the tumor microenvironment is immunosuppressiv...
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
DATE: September 28, 2016TIME: 9:00am Pacific time, 12:00pm Eastern timeNK cells play critical roles in immune defense and reproduction but remain the most poorly under...
In our previous preclinical studies, when neural stem progenitor cells (NS/PCs)-derived from hiPSCs were transplanted into mouse or non-human primate spinal cord injury (SCI) models, long-ter...
DATE: July 20thTIME: 8AM PT, 11AM ET, 5PM CESTTherapies like ipilimumab and nivolumab have shown the potential for approaches that direct the patient’s own immune system aga...
DATE: June 30, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
DATE: January 15, 2016
TIME: 7am EST, 12pm UK, 1pm CET
With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
DATE: October 28th, 2015TIME: 11am Pacific time, 2pm Eastern timeNew discoveries uncover that exposure to current environmental, dietary, behavioral, and medical conditions can significantly...
Using the NSGTM mouse (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ), JAX In Vivo Pharmacology Services has combined the human CD34+ hematopoietic stem cell engrafted NSGTM (hu-CD34 NSGTM) with human pat...
Nanotechnology, the engineering and manufacture of materials at the atomic and molecular scale, is used at BIND Therapeutics to develop novel Accurin™ nanomedicines that utilize cytotoxic age...
Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
There has been a great deal of renewed attention in immuno-oncology over the last decade. Therapies for cancer are being developed, approved, and administered that can either initiate,...
Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. Recent studies show that response to checkpoint blockade does not...
DATE: September 7, 2017TIME: 9:00AM PT, 12:00PM ETThe success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on can...
This seminar will give attendees a full overview of two new Miltenyi cell sorting platforms, the MultiMACS X and the CliniMACS Prodigy and how these instruments can be used in various primary...
DATE: May 2, 2017TIME: 8:00am PT, 11:00am ET, 4:00pm GMT, 5:00pm CETThe natural immune responses that patients develop to their own tumors, as well as therapeutic regimens employin...
DATE: April 25, 2017TIME: 10:00am PT, 1:00pm ETImmunotherapy has emerged as one of the most promising options for the future treatment of a growing number of cancers and is to...
DATE: April 11, 2017TIME: 8:00 AM PT, 11:00 AM ET Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond....
Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance. This adaptive immunity can be reversed to stimulate the endogenous immune re...
New generations of treatments successfully target cancer cell signaling and modulate anti-cancer immunity to improve outcomes for advanced-stage malignancies. Such clinical responses are gove...
The immune system is capable of recognizing tumors and eliminates many early malignant cells. However, tumors evolve to evade immune attack, and the tumor microenvironment is immunosuppressiv...
The ability to measure changes to DNA, RNA, and protein across cell types is crucial to understanding the immune response to the environment or therapeutic treatment. NanoString Technologies...
DATE: September 28, 2016TIME: 9:00am Pacific time, 12:00pm Eastern timeNK cells play critical roles in immune defense and reproduction but remain the most poorly under...
In our previous preclinical studies, when neural stem progenitor cells (NS/PCs)-derived from hiPSCs were transplanted into mouse or non-human primate spinal cord injury (SCI) models, long-ter...
DATE: July 20thTIME: 8AM PT, 11AM ET, 5PM CESTTherapies like ipilimumab and nivolumab have shown the potential for approaches that direct the patient’s own immune system aga...
DATE: June 30, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
Focusing solely on malignant cancer cells and the genes that they express is modestly just a glimpse of the...
Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
DATE: January 15, 2016
TIME: 7am EST, 12pm UK, 1pm CET
With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
Cancer immunotherapy has demonstrated promising results. However, to date, researchers have failed to overcome the complex interplay between the immune system and the immune suppressive tumor...
DATE: October 28th, 2015TIME: 11am Pacific time, 2pm Eastern timeNew discoveries uncover that exposure to current environmental, dietary, behavioral, and medical conditions can significantly...
Using the NSGTM mouse (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ), JAX In Vivo Pharmacology Services has combined the human CD34+ hematopoietic stem cell engrafted NSGTM (hu-CD34 NSGTM) with human pat...
Nanotechnology, the engineering and manufacture of materials at the atomic and molecular scale, is used at BIND Therapeutics to develop novel Accurin™ nanomedicines that utilize cytotoxic age...
Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
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