Synthetic Biology: is an interdisciplinary branch of biology and engineering. The subject combines disciplines from within these domains, such as biotechnology, genetic engineering, molecular biology, molecular engineering, systems biology, membrane science, biophysics, electrical engineering, computer engineering, control engineering and evolutionary biology. Synthetic biology applies these disciplines to build artificial biological systems for research, engineering and medical applications.
RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance. Millipor...
In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
DATE: June 28, 2018TIME: 9:00AM PDTStep up your biologics stability screening with HunkyMany methods for studying protein stability and aggregation are qualitative, which can c...
I will discuss three novel technologies that our laboratory has developed in recent years. In the first part of the talk, I will describe our work on engineering variants of the RNA-guided en...
Synthetic biology is a new set of tools and techniques for engineering biology. Its earliest applications were in biotech-related fields like medicine and agriculture, but today it’s be...
Reliable expression of recombinant proteins in human or CHO cells is essential for many aspects of biomedical research and drug development but is often hampered by low expression yields that...
Triple-negative breast cancer (TNBC) has poor prognosis with frequent relapses and deaths using current standard of care treatments. Metabolic reprograming is now recognized as a fundam...
There is growing consumer and patient demand for products containing cannabidiol (CBD) and other constituents of the cannabis plant, due to their purported medicinal benefits for a myriad of...
DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
DATE: November 29, 2017TIME: 10:00 AM PSTThe three human RAS genes (HRAS, KRAS and NRAS) encode four highly related RAS small GTPases (HRAS, KRAS4A, KRAS4B and NRAS). RAS proteins funct...
DATE: November 14, 2017TIME: 09:00am PST, 12:00pm ESTThe CRISPR-Cas9 system has been adapted to upregulate any gene in its endogenous context, enabling overexpression experiments and av...
DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
DATE: November 2, 2017TIME: 10:00am PDT, 1:00pm EDTA CRISPR Way of Making MiceThe bulk of genetic variation associated with human disease exists in the noncoding genome, much of whi...
DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
The first small molecule inhibitor of the molecular chaperone Heat Shock Protein 90 (HSP90) was identified more than 20 years ago. Upon determination of the drug binding site and clarificatio...
Although the cell is commonly referred to as “the most basic unit of life”, it is actually so complex that despite over 350 years of research we are still far from fully understan...
The human large intestine houses trillions of microorganisms which collectively form the highly diverse microbial community known as the gut microbiota. The gut microbiota performs many funct...
EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series. As a thought-leader in science...
CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering. The delivery of Cas9 plasmid DNA or mR...
RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance. Millipor...
In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
DATE: June 28, 2018TIME: 9:00AM PDTStep up your biologics stability screening with HunkyMany methods for studying protein stability and aggregation are qualitative, which can c...
I will discuss three novel technologies that our laboratory has developed in recent years. In the first part of the talk, I will describe our work on engineering variants of the RNA-guided en...
Synthetic biology is a new set of tools and techniques for engineering biology. Its earliest applications were in biotech-related fields like medicine and agriculture, but today it’s be...
Reliable expression of recombinant proteins in human or CHO cells is essential for many aspects of biomedical research and drug development but is often hampered by low expression yields that...
Triple-negative breast cancer (TNBC) has poor prognosis with frequent relapses and deaths using current standard of care treatments. Metabolic reprograming is now recognized as a fundam...
There is growing consumer and patient demand for products containing cannabidiol (CBD) and other constituents of the cannabis plant, due to their purported medicinal benefits for a myriad of...
DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
DATE: March 22, 2018TIME: 09:00am PST, 12:00pm ESTGlioblastoma (GBM) is the most aggressive primary brain cancer, with nearly universal recurrence after treatment. GBMs are highly heter...
Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
DATE: November 29, 2017TIME: 10:00 AM PSTThe three human RAS genes (HRAS, KRAS and NRAS) encode four highly related RAS small GTPases (HRAS, KRAS4A, KRAS4B and NRAS). RAS proteins funct...
DATE: November 14, 2017TIME: 09:00am PST, 12:00pm ESTThe CRISPR-Cas9 system has been adapted to upregulate any gene in its endogenous context, enabling overexpression experiments and av...
DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
DATE: November 2, 2017TIME: 10:00am PDT, 1:00pm EDTA CRISPR Way of Making MiceThe bulk of genetic variation associated with human disease exists in the noncoding genome, much of whi...
DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
The first small molecule inhibitor of the molecular chaperone Heat Shock Protein 90 (HSP90) was identified more than 20 years ago. Upon determination of the drug binding site and clarificatio...
Although the cell is commonly referred to as “the most basic unit of life”, it is actually so complex that despite over 350 years of research we are still far from fully understan...
The human large intestine houses trillions of microorganisms which collectively form the highly diverse microbial community known as the gut microbiota. The gut microbiota performs many funct...
EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series. As a thought-leader in science...
CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering. The delivery of Cas9 plasmid DNA or mR...
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