Stress is often described as a feeling of being overwhelmed, worried or run-down. Stress can affect people of all ages, genders and circumstances and can lead to both physical and psychological health issues. By definition, stress is any uncomfortable "emotional experience accompanied by predictable biochemical, physiological and behavioral changes." Some stress can be beneficial at times, producing a boost that provides the drive and energy to help people get through situations like exams or work deadlines. However, an extreme amount of stress can have health consequences and adversely affect the immune, cardiovascular, neuroendocrine and central nervous systems.
In this panel discussion, parents of children using cannabis discuss their experience Herah Osborne: A mother’s story about her journey with her twins having Fragile X syndrome an...
March 22, 2018 09:00AM PST, 1:30 pm EST Cortisol plays a central role in the diagnosis of adrenal excess/insufficiency and in theassessment of stress adaptation and relate...
General anesthesia is a drug-induced, reversible condition comprised of five behavioral states: unconsciousness, amnesia (loss of memory), analgesia (loss of pain sensation), akinesia (immobi...
Using Hebbian as well as homeostatic models of brain plasticity, the effects of neurofeedback (NFB) are examined from the theoretical perspective of EEG normalization. Within this framework,...
Most neuropsychiatric diseases involve multifactorial systems characterized by complex interactions among genetic predisposition/resiliency, environmental/social determinants, molecular seque...
Preterm birth (PTB) is the leading cause of infant mortality and morbidity worldwide. Both preterm labor and neonatal injuries have been linked to inflammation. Of all mediators of inflammati...
Compassion fatigue, or the state of chronic stress for those caring for people or animals in distress, can affect anyone working in the lab animal sciences. This can even affect employe...
Assessment of how changes in husbandry affect an animal can be challenging as most common methods of assessment, such as corticosterone levels, are more reliable for assessment of acute stres...
DATE: November 14, 2017TIME: 10:00am PST, 1:00pm ESTSuccessful tumor outgrowth requires the coordination of a variety of cell intrinsic and cell extrinsic signaling events. These events...
Antiplatelet therapy with aspirin (ASA) is widely used in cardiovascular disease (CVD) prevention because it inhibits platelet cyclooxygenase-1 (COX-1) and thromboxane A2 (TXA2)-mediated plat...
The role played by inflammatory hypoxia in biology and treatment of solid tumors will be reviewed. The opportunity to enhance all forms of current anti-tumor therapies through tumor re-...
The first small molecule inhibitor of the molecular chaperone Heat Shock Protein 90 (HSP90) was identified more than 20 years ago. Upon determination of the drug binding site and clarificatio...
Quinolones are one the most commonly prescribed classes of antibacterials in the world and are used to treat a broad variety of Gram-negative and Gram-positive bacterial infections in humans....
A rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...
The realization of the promise of personalized molecular medicine requires efficient development and implementation of novel targeted therapeutics linked to molecular markers able to identify...
Epigenetics refers to the study of nuclear architecture and gene regulation. Epigenetic mechanisms govern many physiological processes such as cell differentiation, x-inactivation, and genomi...
Specialized aggregations of extracellular matrix called perineuronal nets (PNNs) appear during juvenile stages of development and surround primarily fast-spiking, parvalbumin (PV)-containing...
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThe University of Michigan’s Unit for Laboratory Animal Medicine (ULAM) has a diverse Training Core that teaches a wide varie...
DATE: November 23rd, 2016TIME: 8:00AM PT, 11:00AM ETThe structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
In this presentation, we will go over some of the reasons you would want to consider using fluorescence imaging and give a brief introduction to using fluorescent probes for cell structure an...
There is a growing appreciation of the relationship between gut microbiota, and the host in maintaining homeostasis in health and predisposing to disease. Bacterial colonisation of the gut pl...
Our goal - To Understand the Neurobiology of Emotions and Affect and Its Relevance to Psychiatric Disorders. This includes: Understanding basic mechanisms of affect, stre...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
In this panel discussion, parents of children using cannabis discuss their experience Herah Osborne: A mother’s story about her journey with her twins having Fragile X syndrome an...
March 22, 2018 09:00AM PST, 1:30 pm EST Cortisol plays a central role in the diagnosis of adrenal excess/insufficiency and in theassessment of stress adaptation and relate...
General anesthesia is a drug-induced, reversible condition comprised of five behavioral states: unconsciousness, amnesia (loss of memory), analgesia (loss of pain sensation), akinesia (immobi...
Using Hebbian as well as homeostatic models of brain plasticity, the effects of neurofeedback (NFB) are examined from the theoretical perspective of EEG normalization. Within this framework,...
Most neuropsychiatric diseases involve multifactorial systems characterized by complex interactions among genetic predisposition/resiliency, environmental/social determinants, molecular seque...
Preterm birth (PTB) is the leading cause of infant mortality and morbidity worldwide. Both preterm labor and neonatal injuries have been linked to inflammation. Of all mediators of inflammati...
Compassion fatigue, or the state of chronic stress for those caring for people or animals in distress, can affect anyone working in the lab animal sciences. This can even affect employe...
Assessment of how changes in husbandry affect an animal can be challenging as most common methods of assessment, such as corticosterone levels, are more reliable for assessment of acute stres...
DATE: November 14, 2017TIME: 10:00am PST, 1:00pm ESTSuccessful tumor outgrowth requires the coordination of a variety of cell intrinsic and cell extrinsic signaling events. These events...
Antiplatelet therapy with aspirin (ASA) is widely used in cardiovascular disease (CVD) prevention because it inhibits platelet cyclooxygenase-1 (COX-1) and thromboxane A2 (TXA2)-mediated plat...
The role played by inflammatory hypoxia in biology and treatment of solid tumors will be reviewed. The opportunity to enhance all forms of current anti-tumor therapies through tumor re-...
The first small molecule inhibitor of the molecular chaperone Heat Shock Protein 90 (HSP90) was identified more than 20 years ago. Upon determination of the drug binding site and clarificatio...
Quinolones are one the most commonly prescribed classes of antibacterials in the world and are used to treat a broad variety of Gram-negative and Gram-positive bacterial infections in humans....
A rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...
The realization of the promise of personalized molecular medicine requires efficient development and implementation of novel targeted therapeutics linked to molecular markers able to identify...
Epigenetics refers to the study of nuclear architecture and gene regulation. Epigenetic mechanisms govern many physiological processes such as cell differentiation, x-inactivation, and genomi...
Specialized aggregations of extracellular matrix called perineuronal nets (PNNs) appear during juvenile stages of development and surround primarily fast-spiking, parvalbumin (PV)-containing...
Our decisions are governed by a balance between prospective instrumental goal-oriented and retrospective habitual learning strategies. This arbitration is relevant dimensionally across psychi...
DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThe University of Michigan’s Unit for Laboratory Animal Medicine (ULAM) has a diverse Training Core that teaches a wide varie...
DATE: November 23rd, 2016TIME: 8:00AM PT, 11:00AM ETThe structure of chromatin is critical for many aspects of cellular physiology and is considered to be the primary medium to store ep...
In this presentation, we will go over some of the reasons you would want to consider using fluorescence imaging and give a brief introduction to using fluorescent probes for cell structure an...
There is a growing appreciation of the relationship between gut microbiota, and the host in maintaining homeostasis in health and predisposing to disease. Bacterial colonisation of the gut pl...
Our goal - To Understand the Neurobiology of Emotions and Affect and Its Relevance to Psychiatric Disorders. This includes: Understanding basic mechanisms of affect, stre...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
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