Small Molecule: Within the fields of molecular biology and pharmacology, a small molecule is a low molecular weight organic compound that may regulate a biological process, with a size on the order of 1 nm. Most drugs are small molecules.
INTRODUCTION: The recent coincidental emergence of the human microbiota and the Hologneomic Theory of Co-evolution unmasked the “Dual Citizenship” of symbiotic microbes and...
A rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...
The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immen...
Clostridium difficile is a major pathogen responsible for infectious diarrhea in healthcare settings. This presentation will review the data from a study comparing the new Simplexa® C. di...
Background: In March 2014, a molecular cluster of five multidrug resistant Mycobacterium tuberculosis was detected by the Austrian National Reference Laboratory. An investigation was initiate...
Rob Dunn has recently published Never Out of Season, the story of the homogenization of our global food supply and the risks that homogenization poses. He will build on the stories from this...
The immune system is complex and dynamic, focused on defending the body from a host of pathogens ranging from viruses to cancer. A number of different mechanisms have evolved that help the bo...
Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies. Ideally, new approaches would target bacterial pat...
Prokaryotes have long been at war with bacteriophage. The evolutionary pressure of this struggle has led both sides to develop sophisticated defenses. Notably, CRISPR-Cas systems evolved to l...
Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
Diabetes is a debilitating chronic disease that is spirally out of control. Fundamentally, the progressive failure of pancreatic beta cells results in decreased insulin secretion, ultimately ...
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
As reprogramming methodologies have become more reliable and efficient, corresponding improvements were needed in the characterization workflow as well; specifically in terms of the speed, ef...
The commercialization of micro and nanofluidic devices has had promise for providing novel solutions to deliver high throughput, more efficient, integrated biological and chemical analysis to...
Come hear Tecan’s experts discuss how two of their most innovative platforms can empower your lab, every day. The D300e allows rapid delivery of any volume to any well on your ben...
Getting started Equipment Troubleshooting Scale up or scale down your expression runs Tackling difficult-to-express proteins 293 vs. CHO cell expression...
CHO cells are the predominant host for biotherapeutic protein expression with approximately 70% of licensed biologics manufactured in Chinese Hamster Ovary (CHO) cells. The ability to e...
G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...
DATE: March 14, 2017TIME: 8:00AM PST, 11:00AM ESTSurface Plasmon Resonance (SPR) is a widely-used label-free technique to characterize a variety of molecular interactions. SPR is...
Cell growth and regulation involve vast networks of interacting DNAs, RNAs, proteins, lipids and sugars. Through a fundamental strategy of life, these interactions push multiple cellular proc...
Biosensors are now a well-established technology in the study of small molecules. This talk will focus on several aspects of this type of work that biosensor users can be expected to ex...
SPR technology is being improved steadily and today is an essential component in the biopharmaceutical industry. As SPR based assays extract valuable and reliable information at high accuracy...
INTRODUCTION: The recent coincidental emergence of the human microbiota and the Hologneomic Theory of Co-evolution unmasked the “Dual Citizenship” of symbiotic microbes and...
A rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...
The global threat of antimicrobial resistance has been recognized by the World Health Organization, the United Nations and many other expert bodies. The burden of resistant pathogens is immen...
Clostridium difficile is a major pathogen responsible for infectious diarrhea in healthcare settings. This presentation will review the data from a study comparing the new Simplexa® C. di...
Background: In March 2014, a molecular cluster of five multidrug resistant Mycobacterium tuberculosis was detected by the Austrian National Reference Laboratory. An investigation was initiate...
Rob Dunn has recently published Never Out of Season, the story of the homogenization of our global food supply and the risks that homogenization poses. He will build on the stories from this...
The immune system is complex and dynamic, focused on defending the body from a host of pathogens ranging from viruses to cancer. A number of different mechanisms have evolved that help the bo...
Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies. Ideally, new approaches would target bacterial pat...
Prokaryotes have long been at war with bacteriophage. The evolutionary pressure of this struggle has led both sides to develop sophisticated defenses. Notably, CRISPR-Cas systems evolved to l...
Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
Diabetes is a debilitating chronic disease that is spirally out of control. Fundamentally, the progressive failure of pancreatic beta cells results in decreased insulin secretion, ultimately ...
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (iPSCs) as well as engineered heart muscles offer great potential for regenerative applications by CM transplantation, f...
As reprogramming methodologies have become more reliable and efficient, corresponding improvements were needed in the characterization workflow as well; specifically in terms of the speed, ef...
The commercialization of micro and nanofluidic devices has had promise for providing novel solutions to deliver high throughput, more efficient, integrated biological and chemical analysis to...
Come hear Tecan’s experts discuss how two of their most innovative platforms can empower your lab, every day. The D300e allows rapid delivery of any volume to any well on your ben...
Getting started Equipment Troubleshooting Scale up or scale down your expression runs Tackling difficult-to-express proteins 293 vs. CHO cell expression...
CHO cells are the predominant host for biotherapeutic protein expression with approximately 70% of licensed biologics manufactured in Chinese Hamster Ovary (CHO) cells. The ability to e...
G protein coupled receptors (GPCRs) are the targets of 30-40% of all approved drugs. However many approaches successfully applied to drug discovery for soluble protein targets have made a lim...
DATE: March 14, 2017TIME: 8:00AM PST, 11:00AM ESTSurface Plasmon Resonance (SPR) is a widely-used label-free technique to characterize a variety of molecular interactions. SPR is...
Cell growth and regulation involve vast networks of interacting DNAs, RNAs, proteins, lipids and sugars. Through a fundamental strategy of life, these interactions push multiple cellular proc...
Biosensors are now a well-established technology in the study of small molecules. This talk will focus on several aspects of this type of work that biosensor users can be expected to ex...
SPR technology is being improved steadily and today is an essential component in the biopharmaceutical industry. As SPR based assays extract valuable and reliable information at high accuracy...
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