Pain: is felt when special nerves that detect tissue damage send signals to transmit data about the damage along the spinal cord to the brain. These nerves are known as nociceptors. Pain can be chronic or acute and take a variety of forms and severities.
With nearly 9 million covered lives serviced through over 150 medical centers, the VA is one of the largest, unified Healthcare System within the United States. Embedded within this system is...
It has only been in the last 20 years that we, the scientific/medical community, have appreciated the role of the endogenous Cannabinoid system (ECS) in maintaining a healthy immune system an...
Studies have demonstrated how cannabis may contribute to cancer treatment not only by treating symptoms but also by: cancer cell apoptoss, anti-proliferation, anti-metastatic and anti-angioge...
Pain management is the most commonly reported reason for seeking medical cannabis, which is associated with lower opioid use, fewer medication side effects and better quality of life in patie...
General anesthesia is a drug-induced, reversible condition comprised of five behavioral states: unconsciousness, amnesia (loss of memory), analgesia (loss of pain sensation), akinesia (immobi...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Analgesics are commonly employed drugs for perioperative procedures and are required for painful procedures. They include not only non-steroidal anti-inflammatory drugs (NSAIDs) but also opio...
There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the &...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test (...
Acute and chronic pain are often managed with drug therapy, which may include extended use of drug classes such as opioids and benzodiazepines. Pain does not go away, and may intensify...
Novel psychoactive substances (NPS) emerged in the United States around 2000. Initially, synthetic cannabinoids and stimulants prevailed. Now, designer opioids, benzodiazepines an...
Many Americans have succumbed to the scare tactics of the dermatological community, and avoid sunlight for fear of skin cancer and premature aging. Therefore, most of us suffer from vitamin D...
DATE: September 21, 2017TIME: 8:00AM PSTBoard-certified hematologist-oncologist Ola Landgren, MD, PhD, will review how vague symptoms (fatigue, bone pain, back pain) are linked to...
DATE: May 17, 2017TIME: 9:00am PT, 12:00pm ETPracticing Internist and vitamin D researcher Gregory A. Plotnikoff, MD, MTS, FACP, will review how new testing for 1,25-Dihydroxy...
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETMeloxicam is an analgesic NSAID commonly used in mice. Anecdotal evidence supports the use of alternative delivery methods for analgesics...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 6:00am PT, 9:00 ETSeveral regulatory bodies require that animals used in biomedical and behavioral research exposed to procedures that may cause more th...
Bulk analysis often leads to conclusions that assume averages reflect the dominant biological mechanism operating within an entire population. To fully understand how cellular heterogeneity c...
There have been significant increases in emergency room visits across the US and delays in the ED leads to poor outcomes. There is an association between waiting times and short term mo...
With nearly 9 million covered lives serviced through over 150 medical centers, the VA is one of the largest, unified Healthcare System within the United States. Embedded within this system is...
It has only been in the last 20 years that we, the scientific/medical community, have appreciated the role of the endogenous Cannabinoid system (ECS) in maintaining a healthy immune system an...
Studies have demonstrated how cannabis may contribute to cancer treatment not only by treating symptoms but also by: cancer cell apoptoss, anti-proliferation, anti-metastatic and anti-angioge...
Pain management is the most commonly reported reason for seeking medical cannabis, which is associated with lower opioid use, fewer medication side effects and better quality of life in patie...
General anesthesia is a drug-induced, reversible condition comprised of five behavioral states: unconsciousness, amnesia (loss of memory), analgesia (loss of pain sensation), akinesia (immobi...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Analgesics are commonly employed drugs for perioperative procedures and are required for painful procedures. They include not only non-steroidal anti-inflammatory drugs (NSAIDs) but also opio...
There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the &...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test (...
Acute and chronic pain are often managed with drug therapy, which may include extended use of drug classes such as opioids and benzodiazepines. Pain does not go away, and may intensify...
Novel psychoactive substances (NPS) emerged in the United States around 2000. Initially, synthetic cannabinoids and stimulants prevailed. Now, designer opioids, benzodiazepines an...
Many Americans have succumbed to the scare tactics of the dermatological community, and avoid sunlight for fear of skin cancer and premature aging. Therefore, most of us suffer from vitamin D...
DATE: September 21, 2017TIME: 8:00AM PSTBoard-certified hematologist-oncologist Ola Landgren, MD, PhD, will review how vague symptoms (fatigue, bone pain, back pain) are linked to...
DATE: May 17, 2017TIME: 9:00am PT, 12:00pm ETPracticing Internist and vitamin D researcher Gregory A. Plotnikoff, MD, MTS, FACP, will review how new testing for 1,25-Dihydroxy...
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETMeloxicam is an analgesic NSAID commonly used in mice. Anecdotal evidence supports the use of alternative delivery methods for analgesics...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 6:00am PT, 9:00 ETSeveral regulatory bodies require that animals used in biomedical and behavioral research exposed to procedures that may cause more th...
Bulk analysis often leads to conclusions that assume averages reflect the dominant biological mechanism operating within an entire population. To fully understand how cellular heterogeneity c...
There have been significant increases in emergency room visits across the US and delays in the ED leads to poor outcomes. There is an association between waiting times and short term mo...
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