Molecular Diagnostics: Molecular diagnostic tests detect specific sequences in DNA or RNA that may or may not be associated with disease, including single nucleotide polymorphism (SNP), deletions, rearrangements, insertions and others. By analysing the specifics of the patient and their disease, molecular diagnostics offers the prospect of personalized medicine. These tests are useful in a range of medical specialisms, including infectious disease, oncology, human leucocyte antigen typing, coagulation, and pharmacogenomics-the genetic prediction of which drugs will work best.
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High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance. Millipor...
Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
With over 265,000 new cases per year and over 50,000 deaths, breast and ovarian cancers represent a significant health burden in the USA. Prior work has demonstrated that CD4 helper T c...
Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
DATE: September 27, 2018TIME: 8:00AM PDTRecent advances in phage display for molecular evolution incorporate deep sequencing to enable greater library coverage. However, severe gap...
DATE: September 20 2018TIME: 11:00am EDT, 5:00pm CEST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-call...
DATE: September 20, 2018TIME: 10:00am CEST, 4:00pm CST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-called “...
DATE: August 9, 2018TIME: 8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
DATE: August 7, 2018TIME: 08:00AM PDT, 11:00AM EDTWe are currently at an exciting precipice in clinical oncology management, where an increased rate of biomarker identification is drivi...
DATE: July 11, 2018TIME: 10:00AM PDT, 1:00PM EDTSexually transmitted diseases remain a major global public health burden despite the availability of effective prevention strategies to d...
The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...