Medicine is both a science and a practice involving caring for patients by diagnosing and managing injury, disease, and illness. Surgery is a medical specialty which uses operative tetchiness to treat injury, disease, or illness, or alter the function or appearance of a part of the body.
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 7:30am PT, 10:30am ETMany of us who believe in the importance of aseptic rodent surgery have lived through the frustration of trying to implement rodent asep...
DATE: December 7, 2016TIME: 8:00am PT, 11:00am ET1,25-dihydroxyvitamin D (1,25[OH]2D) is the active, hormonal form of vitamin D. It is produced from its precursor (vitamin D) by two hyd...
DATE: December 1, 2016TIME: 8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
Over the past 6 years, a number of agents, all mechanistically different, have been approved with a statistically significant survival benefit as monotherapy for treatment of metastatic castr...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Cataract, or vision loss due to clouding of the eye’s lens, is a large and costly international problem. Over 80 million people currently have low vision due to cataract. Cataracts can ...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
Schizophrenia, depression, bipolar disorder are all uniquely human conditions. Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
Given the challenges of replicating Parkinson’s disease in animal models, returning to models that are human-based and highly clinically characterized may provide the most successful pa...
The adolescent brain has been forged by evolution to have different features than those of a child or an adult, but it is not broken or defective. Phenomenal ability to adapt to environ...
Drug addiction is a chronically relapsing disorder characterized by compulsive drug use despite catastrophic personal consequences (e.g., loss of family, job) and even when the substance is n...
A key goal in psychiatry is to build new diagnostic, therapeutic and translational tools and capacity to reduce the impact of emerging mental disorders in young people on survival, distress,...
Schizophrenia (Sz) is a major mental disorder that affects ~1% of the population. Although traditional models of Sz focused on dopaminergic dysfunction, newer models increasingly implic...
In this presentation, Arvid Carlsson, who was awarded the Nobel prize in 2000 for his discovery of the transmitter role of dopamine, will be interviewed by Elias Eriksson. The following aspec...
Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
Innovation in Psychopharmacology is Dead. Long Live Innovation in Psychopharmacology! What’s going on in our field? Priorities of Big Pharma shifting away fr...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
The use of laboratory animals requires education and training of persons who are to design and/or perform animal experiments. It is essential for these persons to practice various procedures...
Cancer-derived extracellular vesicles (EVs) play an important role in cancer progression and metastasis. They can be identified in biological fluids thus providing appealing candidates for no...
Stage IV melanoma carried a 24 month life expectancy three short years ago. That is what T.J. Sharpe’s first oncologist told him he was facing, after a visit to the ER for a fever turne...
This presentation discusses the advantages and disadvantages of robotic surgery. The initial goals for a robotic prostatectomy will be discussed as well as patient expectations and outcomes.&...
The management of prostate cancer (PCa) continues to evolve and does so at a rapid rate. Research and technological developments continue to refine our definitions and management of this comp...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 7:30am PT, 10:30am ETMany of us who believe in the importance of aseptic rodent surgery have lived through the frustration of trying to implement rodent asep...
DATE: December 7, 2016TIME: 8:00am PT, 11:00am ET1,25-dihydroxyvitamin D (1,25[OH]2D) is the active, hormonal form of vitamin D. It is produced from its precursor (vitamin D) by two hyd...
DATE: December 1, 2016TIME: 8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
Over the past 6 years, a number of agents, all mechanistically different, have been approved with a statistically significant survival benefit as monotherapy for treatment of metastatic castr...
Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Cataract, or vision loss due to clouding of the eye’s lens, is a large and costly international problem. Over 80 million people currently have low vision due to cataract. Cataracts can ...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
Schizophrenia, depression, bipolar disorder are all uniquely human conditions. Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
Given the challenges of replicating Parkinson’s disease in animal models, returning to models that are human-based and highly clinically characterized may provide the most successful pa...
The adolescent brain has been forged by evolution to have different features than those of a child or an adult, but it is not broken or defective. Phenomenal ability to adapt to environ...
Drug addiction is a chronically relapsing disorder characterized by compulsive drug use despite catastrophic personal consequences (e.g., loss of family, job) and even when the substance is n...
A key goal in psychiatry is to build new diagnostic, therapeutic and translational tools and capacity to reduce the impact of emerging mental disorders in young people on survival, distress,...
Schizophrenia (Sz) is a major mental disorder that affects ~1% of the population. Although traditional models of Sz focused on dopaminergic dysfunction, newer models increasingly implic...
In this presentation, Arvid Carlsson, who was awarded the Nobel prize in 2000 for his discovery of the transmitter role of dopamine, will be interviewed by Elias Eriksson. The following aspec...
Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
Innovation in Psychopharmacology is Dead. Long Live Innovation in Psychopharmacology! What’s going on in our field? Priorities of Big Pharma shifting away fr...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
The use of laboratory animals requires education and training of persons who are to design and/or perform animal experiments. It is essential for these persons to practice various procedures...
Cancer-derived extracellular vesicles (EVs) play an important role in cancer progression and metastasis. They can be identified in biological fluids thus providing appealing candidates for no...
Stage IV melanoma carried a 24 month life expectancy three short years ago. That is what T.J. Sharpe’s first oncologist told him he was facing, after a visit to the ER for a fever turne...
This presentation discusses the advantages and disadvantages of robotic surgery. The initial goals for a robotic prostatectomy will be discussed as well as patient expectations and outcomes.&...
The management of prostate cancer (PCa) continues to evolve and does so at a rapid rate. Research and technological developments continue to refine our definitions and management of this comp...
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