Lab animal medicine in a branch of veterinary science involving the animals used for laboratory research. Lab animal medicine can encompass general veterinary care, medical treatment, surgical procedures, to care for the well-being of laboratory animals and also advance research. Mice, rats, guinea pigs, monkeys, rabbits, cats, dogs, and pigs are some examples of animals that can be used for laboratory research models.
DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
When the human genome was sequenced almost 15 years ago, it was a milestone for the understanding of an individual’s genome. However to fully understand a disease, millions of ind...
DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
Triple-negative breast cancer (TNBC) has poor prognosis with frequent relapses and deaths using current standard of care treatments. Metabolic reprograming is now recognized as a fundam...
The cannabis industry as a whole is under considerable scrutiny. Finger-pointing and blame regarding inaccurate product labels run rampant. Media outlets have often faulted the sk...
Analysis of pesticides in cannabis is essential to protect the public health, especially medical cannabis patients. Sensitive and selective measurement is required in order to provide confide...
With 46 states having some form of medical cannabis program to date, we are experiencing a “green rush” where everyone is trying to sell some type of cannabis products to parents/...
The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
Compassion fatigue, or the state of chronic stress for those caring for people or animals in distress, can affect anyone working in the lab animal sciences. This can even affect employe...
Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Assessment of how changes in husbandry affect an animal can be challenging as most common methods of assessment, such as corticosterone levels, are more reliable for assessment of acute stres...
There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize...
Introduction:The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous sys...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the &...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test (...
Conspecific aggression is a common problem amongst laboratory housed male mice. While C57BL/6 are not the most aggressive strain we house, they are exceedingly common, and dealing with...
There is a considerable interest and need for evidence-based recommendations regarding the social housing of laboratory rabbits. This presentation will review the principles surrounding the s...
DATE: November 2, 2017TIME: 10:00am PDT, 1:00pm EDTA CRISPR Way of Making MiceThe bulk of genetic variation associated with human disease exists in the noncoding genome, much of whi...
The continuous generation of blood cells throughout life relies on the existence of hematopoietic stem cells (HSC) generated during embryogenesis. Given the importance of HSC transplantation...
Ductal cells share several markers with pancreatic embryonic progenitors, suggesting that ductal cells could be the closest lineage to an adult progenitor in the pancreas, thus their stem-lik...
DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
When the human genome was sequenced almost 15 years ago, it was a milestone for the understanding of an individual’s genome. However to fully understand a disease, millions of ind...
DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
Triple-negative breast cancer (TNBC) has poor prognosis with frequent relapses and deaths using current standard of care treatments. Metabolic reprograming is now recognized as a fundam...
The cannabis industry as a whole is under considerable scrutiny. Finger-pointing and blame regarding inaccurate product labels run rampant. Media outlets have often faulted the sk...
Analysis of pesticides in cannabis is essential to protect the public health, especially medical cannabis patients. Sensitive and selective measurement is required in order to provide confide...
With 46 states having some form of medical cannabis program to date, we are experiencing a “green rush” where everyone is trying to sell some type of cannabis products to parents/...
The study of rare, neurological disorder and the development of effect treatments can pose many unique challenges. A paucity of scientists working on these disorders often limits forward prog...
Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
Compassion fatigue, or the state of chronic stress for those caring for people or animals in distress, can affect anyone working in the lab animal sciences. This can even affect employe...
Preclinical translational imaging, and specifically molecular imaging methods such as positron emission tomography (PET) or single photon emission computed tomography (SPECT) as well as magne...
The translation gap in biomedical research can be attributed in part to differences in how outcomes are assessed in preclinical research and in the clinic. Reasons for these mismatches includ...
Assessment of how changes in husbandry affect an animal can be challenging as most common methods of assessment, such as corticosterone levels, are more reliable for assessment of acute stres...
There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize...
Introduction:The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous sys...
Compassion Fatigue can affect all those that care for and work with laboratory animals, including husbandry staff, veterinary staff, researchers, and other support staff. It is known as the &...
The ability to rapidly and accurately identify pain in mice is critical for providing them optimal care and welfare. To meet this need, we developed and validated the Grooming Transfer Test (...
Conspecific aggression is a common problem amongst laboratory housed male mice. While C57BL/6 are not the most aggressive strain we house, they are exceedingly common, and dealing with...
There is a considerable interest and need for evidence-based recommendations regarding the social housing of laboratory rabbits. This presentation will review the principles surrounding the s...
DATE: November 2, 2017TIME: 10:00am PDT, 1:00pm EDTA CRISPR Way of Making MiceThe bulk of genetic variation associated with human disease exists in the noncoding genome, much of whi...
The continuous generation of blood cells throughout life relies on the existence of hematopoietic stem cells (HSC) generated during embryogenesis. Given the importance of HSC transplantation...
Ductal cells share several markers with pancreatic embryonic progenitors, suggesting that ductal cells could be the closest lineage to an adult progenitor in the pancreas, thus their stem-lik...
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