Imaging: the technique and process of creating visual representations of the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging.
1. Identify 3 barriers to immune cell response to cancer 2. List 3 approaches to overcome immunosuppressive barriers to bolster the immune response to cancer 3. Explain how fusion proteins c...
Almost unidimensional in their primordial existence as single cells, multicellular organisms quickly develop into complex 3D architectures and machineries composed of multiple cells and tiss...
Madin Darby Canine Kidney (MDCK) cells can form a polarized epithelial layer in culture. We and others have observed that these layers are frequently characterized by extralayer cells, posit...
During organismal development, differential regulation of the cell cycle is critical to many cell biological processes, including cell migration, cell fate specification and differentiation....
The transport properties of biomolecules in cells can reveal a great deal about the functional interactions regulating cells at the molecular level. Various biophysical methods have been dev...
LED illumination has become more prominent in microscopy for both fluorescence and transmitted applications over the past few years. Today, LEDs provide many benefits over mercury and metal...
Programmed death-1 (PD-1) inhibits T and B cell function upon ligand binding. PD-1 blockade revolutionized cancer treatment, and while numerous patients respond, some develop autoimmune-like...
The mammary gland is a unique organ that develops predominantly after birth and undergoes dramatic remodelling in reproductive phases. Macrophages have been implicated in mammary gland funct...
Confocal microscopes (and related instruments such as Two-Photon) are often used for the most rigorous quantitative fluorescence microscopy measurements. Most confocal users are aware of the...
How organisms control organ size is a fundamental question in developmental and regenerative biology. The underlaying mechanisms are not well defined. For instance, we don’t fully unde...
Microtubules (MTs) are dynamic cytoskeleton polymers forming a polarized intracellular network that provides structural support, facilitates intracellular transport and drives chromosome seg...
One of the main challenges in cancer immunotherapy is the resistance to I-O therapies. Primary resistance can occur before treatment and acquired resistance can occur in patients who respond...
Centriole assembly requires a small number of conserved proteins. The precise pathway of centriole assembly has been difficult to study, as the lack of any one of the core assembly proteins&...
B cells have recently come into vogue as important contributors to the anti-tumor immune response in cancer patients. Specifically, B cells and the immune structures in which they reside (te...
NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
Multi-colour electron microscopy (MCEM) combines ultrastructural electron data with elemental information, transforming traditionally grey scale electron micrographs into colourful images th...
Learning Objectives: 1. Define applications of approved and experimental (multiplexing IF) biomarker assessment in Immuno-Oncology 2. Define bottlenecks and areas of improvement to current t...
Platinum-based chemotherapy has been the cornerstone for treating metastatic urothelial cancer, which compromises the majority of bladder cancer. While urothelial cancer is chemosensitive, p...
Recent advances in high-throughput single-cell transcriptomics and epigenomics methods allow to measure the expression of thousands of genes and identify the gene transcriptional regulation...
Recent developments in reporters for calcium, voltage, and neurotransmitters, together with interest in understanding neuronal circuit function, have driven the development of methods for fa...
1. Identify 3 barriers to immune cell response to cancer 2. List 3 approaches to overcome immunosuppressive barriers to bolster the immune response to cancer 3. Explain how fusion proteins c...
Almost unidimensional in their primordial existence as single cells, multicellular organisms quickly develop into complex 3D architectures and machineries composed of multiple cells and tiss...
Madin Darby Canine Kidney (MDCK) cells can form a polarized epithelial layer in culture. We and others have observed that these layers are frequently characterized by extralayer cells, posit...
During organismal development, differential regulation of the cell cycle is critical to many cell biological processes, including cell migration, cell fate specification and differentiation....
The transport properties of biomolecules in cells can reveal a great deal about the functional interactions regulating cells at the molecular level. Various biophysical methods have been dev...
LED illumination has become more prominent in microscopy for both fluorescence and transmitted applications over the past few years. Today, LEDs provide many benefits over mercury and metal...
Programmed death-1 (PD-1) inhibits T and B cell function upon ligand binding. PD-1 blockade revolutionized cancer treatment, and while numerous patients respond, some develop autoimmune-like...
The mammary gland is a unique organ that develops predominantly after birth and undergoes dramatic remodelling in reproductive phases. Macrophages have been implicated in mammary gland funct...
Confocal microscopes (and related instruments such as Two-Photon) are often used for the most rigorous quantitative fluorescence microscopy measurements. Most confocal users are aware of the...
How organisms control organ size is a fundamental question in developmental and regenerative biology. The underlaying mechanisms are not well defined. For instance, we don’t fully unde...
Microtubules (MTs) are dynamic cytoskeleton polymers forming a polarized intracellular network that provides structural support, facilitates intracellular transport and drives chromosome seg...
One of the main challenges in cancer immunotherapy is the resistance to I-O therapies. Primary resistance can occur before treatment and acquired resistance can occur in patients who respond...
Centriole assembly requires a small number of conserved proteins. The precise pathway of centriole assembly has been difficult to study, as the lack of any one of the core assembly proteins&...
B cells have recently come into vogue as important contributors to the anti-tumor immune response in cancer patients. Specifically, B cells and the immune structures in which they reside (te...
NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
Multi-colour electron microscopy (MCEM) combines ultrastructural electron data with elemental information, transforming traditionally grey scale electron micrographs into colourful images th...
Learning Objectives: 1. Define applications of approved and experimental (multiplexing IF) biomarker assessment in Immuno-Oncology 2. Define bottlenecks and areas of improvement to current t...
Platinum-based chemotherapy has been the cornerstone for treating metastatic urothelial cancer, which compromises the majority of bladder cancer. While urothelial cancer is chemosensitive, p...
Recent advances in high-throughput single-cell transcriptomics and epigenomics methods allow to measure the expression of thousands of genes and identify the gene transcriptional regulation...
Recent developments in reporters for calcium, voltage, and neurotransmitters, together with interest in understanding neuronal circuit function, have driven the development of methods for fa...