Human research is scientific research conducted with human subjects in an effort to improve health. Human research can involve people directly, but it can also utilize specimens or data from people. Research can be aimed at developing a new drug or therapy or improving a diagnostic or therapeutic technique.
The advent of the microarray technology in 2000 has paved the way for advanced translational research methods that use molecular markers such as microRNA, proteins, metabolites and copy numbe...
Cell death is involved in diseases such as cancer and neurodegeneration, and also has a natural role in the development of multicellular organisms. Although apoptosis has been well defined, a...
Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
On January 20, 2015, President Obama announced the Precision Medicine Initiative® (PMI) (link is external) in his State of the Union address. Through advances in research, technology and...
One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
Understanding disease at a deeper level so that it can be targeted more precisely is the essence of precision medicine. Rapid technological advance, particularly in genomics and sensor-based...
In December 2012 the UK Prime Minister announced the 100,000 genomes project to introduce whole genome sequencing for treatment into the UK National Health Service (NHS) o...
Precision medicine promises a more effective approach to disease treatment and management. It is based on analyzing mutations of disease samples to unlock mechanisms of disease development an...
Personalised Healthcare is essential to AstraZeneca’s approach to drug development and is adopted by more than 80% of drug products in clinical development. Selection of the right patie...
Science continues to evolve at a rapid pace. Our understanding of laboratory animal behavior and welfare is also growing. The biomedical research community continues to receive criticisms fro...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
The environment has been found to be a major contributor to data variability and many aspects of the laboratory environment are stressful to rodents and do not accurately reflect the human ex...
The fate of all but a very few laboratory animals is to be killed at the end of their experimental lives. There is a moral responsibility to give the animals used in science a humane death by...
In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
DATE: February 2nd, 2016
TIME: 9am pacific time, 12pm eastern time
What is the most appropriate technology to empower your research?
Next generation sequencing (NGS) for RN...
Innate Lymphoid Cells (ILC) are lymphocytes that share the same morphological features of classical lymphocytes. They lack specific antigen receptors (Spits and Cupedo Annu Rev Immunol 2012)....
Cancer-derived extracellular vesicles (EVs) play an important role in cancer progression and metastasis. They can be identified in biological fluids thus providing appealing candidates for no...
The advent of the microarray technology in 2000 has paved the way for advanced translational research methods that use molecular markers such as microRNA, proteins, metabolites and copy numbe...
Cell death is involved in diseases such as cancer and neurodegeneration, and also has a natural role in the development of multicellular organisms. Although apoptosis has been well defined, a...
Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
On January 20, 2015, President Obama announced the Precision Medicine Initiative® (PMI) (link is external) in his State of the Union address. Through advances in research, technology and...
One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
Understanding disease at a deeper level so that it can be targeted more precisely is the essence of precision medicine. Rapid technological advance, particularly in genomics and sensor-based...
In December 2012 the UK Prime Minister announced the 100,000 genomes project to introduce whole genome sequencing for treatment into the UK National Health Service (NHS) o...
Precision medicine promises a more effective approach to disease treatment and management. It is based on analyzing mutations of disease samples to unlock mechanisms of disease development an...
Personalised Healthcare is essential to AstraZeneca’s approach to drug development and is adopted by more than 80% of drug products in clinical development. Selection of the right patie...
Science continues to evolve at a rapid pace. Our understanding of laboratory animal behavior and welfare is also growing. The biomedical research community continues to receive criticisms fro...
Working with animals carries legal, scientific and ethical responsibilities. These responsibilities merge as we strive to humanely use the least number of animals necessary to provide t...
The environment has been found to be a major contributor to data variability and many aspects of the laboratory environment are stressful to rodents and do not accurately reflect the human ex...
The fate of all but a very few laboratory animals is to be killed at the end of their experimental lives. There is a moral responsibility to give the animals used in science a humane death by...
In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
Public, legal & ethical acceptability of animal research not only warrants respect for animal welfare & the 3Rs, but also that the perceived benefits can outweigh the pain, discomfort...
Animal models have provided an important tool to help make the decision to take potential therapies from preclinical studies to humans. In the past several years, the strong reliance of the p...
Surgerized animals play a crucial role in preclinical research aimed at drug and medical device discovery into treatments for humans. When implementing new in-house surgical models to perform...
Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
Noise and vibration are very effective activators of stress pathways in rodent models that can increase variability in animal models, thereby confounding virtually every area of biomedical an...
DATE: February 2nd, 2016
TIME: 9am pacific time, 12pm eastern time
What is the most appropriate technology to empower your research?
Next generation sequencing (NGS) for RN...
Innate Lymphoid Cells (ILC) are lymphocytes that share the same morphological features of classical lymphocytes. They lack specific antigen receptors (Spits and Cupedo Annu Rev Immunol 2012)....
Cancer-derived extracellular vesicles (EVs) play an important role in cancer progression and metastasis. They can be identified in biological fluids thus providing appealing candidates for no...
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