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Hepatic models
Hepatic models are pre-clinical systems used to research diseases involving the liver. Examples of hepatic models include "liver-on-a-chip", a microfluidic replica or the liver microenvironment, and liver organoids, a collection of various cells that display liver-specific functions and structural organization. Hepatic models have been used for disease modeling, drug development, and clinical application.
MAY 01, 2017 | 8:00 AM
Neurons derived from human pluripotent stem cells (hPSCs) and primary rodent neurons both are excellent resources for disease modeling and drug screening. Human PSCs derived neural stem...
FEB 08, 2017 | 3:00 PM
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETThe Eastern woodchuck (Marmota monax) is a large, burrowing rodent with native territories throughout parts of the US and Canada. Woodchu...
SEP 08, 2016 | 12:00 PM
Virus Ecology is a field that is gaining momentum, fueled in part by metagenomic studies from many environments previously ignored. Biodiversity studies of plant viruses show that they...
AUG 30, 2016 | 8:00 AM
In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-...
AUG 30, 2016 | 8:00 AM
Neurons derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), are excellent resources for disease modeling and d...
SEP 30, 2015 | 12:00 PM
Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
FEB 06, 2014 | 6:00 AM
The utility of dried blood spot (DBS) sampling technology for rodent colony health monitoring was investigated using a two-tiered approach. In the first approach, groups of mice and rats were...