GPCR: G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in eukaryotes. These cell surface receptors act like an inbox for messages in the form of light energy, peptides, lipids, sugars, and proteins. Such messages inform cells about the presence or absence of life-sustaining light or nutrients in their environment, or they convey information sent by other cells.
DATE:April 30, 2020 TIME: 8AM PT, 11AM ET, 4PM BST, 5PM CEST Cytokinesis is the physical separation of two cells that occurs after the completion of mitosis. The mechanism underlying it is v...
DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
DATE: January 29, 2019 TIME: 9:00am PST Plasma membrane proteins are a difficult subset of proteins to solubilize, purify, quantify, and detect, largely due to the challenge of extracting th...
DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
DATE: December 10, 2019TIME: 8:00am PST, 11:00am EST In this presentation, we demonstrate the performance of a new range of Expi293 components, including engineered Expi293 cell...
DATE: September 25, 2019TIME: 8:00am PT, 11:00am ET This talk will focus on strategies for optimizing expression levels of membrane proteins using the Gibcoâ„¢ Expi293â„¢ and ExpiCHOâ„¢ Expres...
DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
AstraZeneca has an ambition to create a porous organisation, seamlessly collaborating with external partners. This desire has led to the establishment of the AstraZeneca-MRC UK Centre for Lea...
G protein-coupled receptors (GPCRs) regulate virtually all known physiological processes and are a premier class of drug targets. However, a detailed mechanistic understanding of their...
GPCRs constitute the largest receptor family in the human genome. Over the years they have proven themselves to be druggable targets accounting for about 1/3 of all drugs on the market today....
Structure based drug design is now well established as a highly efficient approach in pharmaceutical research. The approach uses atomic level detail structures of target proteins, most...
G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
Rapid, accurate estimation of relative ligand affinities offers the potential to allow computational methods to direct drug design and development. Towards this goal we have developed t...
The distinction between "complementary" and "companion" diagnostics tests confuse many physicians and healthcare professionals. Panelists Professor Thomas Webster (Northea...
One-third of FDA-approved drugs target G protein-coupled receptors (GPCRs), transmembrane cell surface proteins that recognize small molecules and polypeptides with diverse chemical scaffolds...
DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series. As a thought-leader in science...
DATE: July 20, 2017TIME: 10:00am PT, 1:00pm ETPart 1 - Daniel Beacham: Case study showing how CyQUANT Direct Cell Proliferation and Fluo-4 calcium imaging assays were us...
EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series. As a thought-leader in science our first commit...
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...
Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...
DATE:April 30, 2020 TIME: 8AM PT, 11AM ET, 4PM BST, 5PM CEST Cytokinesis is the physical separation of two cells that occurs after the completion of mitosis. The mechanism underlying it is v...
DATE: March 24, 2020 TIME: 10:00 am PDT, 1:00pm EDT The Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Rece...
DATE: January 29, 2019 TIME: 9:00am PST Plasma membrane proteins are a difficult subset of proteins to solubilize, purify, quantify, and detect, largely due to the challenge of extracting th...
DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
DATE: December 10, 2019TIME: 8:00am PST, 11:00am EST In this presentation, we demonstrate the performance of a new range of Expi293 components, including engineered Expi293 cell...
DATE: September 25, 2019TIME: 8:00am PT, 11:00am ET This talk will focus on strategies for optimizing expression levels of membrane proteins using the Gibcoâ„¢ Expi293â„¢ and ExpiCHOâ„¢ Expres...
DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
AstraZeneca has an ambition to create a porous organisation, seamlessly collaborating with external partners. This desire has led to the establishment of the AstraZeneca-MRC UK Centre for Lea...
G protein-coupled receptors (GPCRs) regulate virtually all known physiological processes and are a premier class of drug targets. However, a detailed mechanistic understanding of their...
GPCRs constitute the largest receptor family in the human genome. Over the years they have proven themselves to be druggable targets accounting for about 1/3 of all drugs on the market today....
Structure based drug design is now well established as a highly efficient approach in pharmaceutical research. The approach uses atomic level detail structures of target proteins, most...
G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
Rapid, accurate estimation of relative ligand affinities offers the potential to allow computational methods to direct drug design and development. Towards this goal we have developed t...
The distinction between "complementary" and "companion" diagnostics tests confuse many physicians and healthcare professionals. Panelists Professor Thomas Webster (Northea...
One-third of FDA-approved drugs target G protein-coupled receptors (GPCRs), transmembrane cell surface proteins that recognize small molecules and polypeptides with diverse chemical scaffolds...
DATE: October 24, 2017TIME: 09:00am PDT, 12:00pm EDTDoes your work involve disease models? Do you have a need to introduce specific genomic changes in the cells of your choice? Do you w...
EVENT DETAILS:DATE: July 25, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series. As a thought-leader in science...
DATE: July 20, 2017TIME: 10:00am PT, 1:00pm ETPart 1 - Daniel Beacham: Case study showing how CyQUANT Direct Cell Proliferation and Fluo-4 calcium imaging assays were us...
EVENT DETAILS:DATE: May 16, 2017TIME: 9:00am PT, Noon ETThermo Fisher Scientific is proud to present the SyncD3 webinar series. As a thought-leader in science our first commit...
CALIXAR has developed an innovative detergent/surfactant based approach consisting on native isolation and stabilization of therapeutic membrane protein targets such as GPCRs, ion channels, t...
Developing therapies for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficaciou...