Genomic analysis is the identification, measurment, and/or comparison of genomic features (like DNA sequences) on a genomic (i.e., the study of all of a person's genes) scale.
DATE: October 25, 2017TIME: 06:00am PDT, 09:00am EDTThis is the third topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’.Repetitive DNA...
DATE: October 19, 2017TIME: 7:00 AM PDT, 10:00 AM EDT, 4:00 PM CETThis is the second topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’...
The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
The promise of precision and personalized medicine is rooted in accurate, highly sensitive, and specific disease biomarkers. This is particularly true for cancer-a disease characterized by ma...
The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
Acral lentiginous melanoma (ALM) is a rare sun-shielded melanoma subtype associated with worse survival than cutaneous melanoma (CM), a more common form of skin cancer linked to exposure to u...
We developed two computational methods, CARE and TIDE, to predict response and resistance to targeted therapies and immunotherapies. CARE infers gene signatures of targeted therapy response b...
Pancreatic cancer is one of the “deadly” cancers, defined as those with a 5-year relative survival rate of less than 50%. Although ranking 12th in terms of incidence, it is...
Nanopore sequencing has enormous potential for application to cancer, but specifically offers advantages into two main arenas, epigenetics and structural variation. Methylation is well-known...
There has been a great deal of renewed attention in immuno-oncology over the last decade. Therapies for cancer are being developed, approved, and administered that can either initiate,...
DATE: October 10, 2017TIME: 7:00 AM PT, 10:00 AM ETQuality assessment of monoclonal antibodies can be a bottleneck in biopharmaceutical workflows because of the complexity and length of...
Traditional high throughput screening (HTS) assays for neuronal targets employ non-human primary neuronal cells due to the scale necessary for HTS. Isolation of mouse primary neurons can be u...
The Resource Identification Initiative supports NIH's new guidelines for Rigor and Transparency as these apply in biomedical publications. Authors are instructed to authenticate key biolo...
Stem cells can self-renew and differentiate into multiple different cell types. Engineering of stem cells has enabled new methods to study development and organogenesis in humans as well as d...
I will present my lab’s effort on studying and manipulating RNA processing, with particular emphasis on using CRISPR/Cas systems for targeting RNA in living cells in diseases such as my...
The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
DATE: September 20, 2017TIME: 11:30AM PDTCoffea arabica accounts for 70% of world coffee production and is threatened by various biotic and abiotic factors. In this webinar, Dr. Susan S...
Genome sequencing can be used to discover new pathogens but it can also be used to monitor known ones. This is known as genomic surveillance and it becoming an increasingly important tool in...
Quinolones are one the most commonly prescribed classes of antibacterials in the world and are used to treat a broad variety of Gram-negative and Gram-positive bacterial infections in humans....
A rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...
Background: In March 2014, a molecular cluster of five multidrug resistant Mycobacterium tuberculosis was detected by the Austrian National Reference Laboratory. An investigation was initiate...
Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies. Ideally, new approaches would target bacterial pat...
Prokaryotes have long been at war with bacteriophage. The evolutionary pressure of this struggle has led both sides to develop sophisticated defenses. Notably, CRISPR-Cas systems evolved to l...
DATE: October 25, 2017TIME: 06:00am PDT, 09:00am EDTThis is the third topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’.Repetitive DNA...
DATE: October 19, 2017TIME: 7:00 AM PDT, 10:00 AM EDT, 4:00 PM CETThis is the second topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’...
The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
The promise of precision and personalized medicine is rooted in accurate, highly sensitive, and specific disease biomarkers. This is particularly true for cancer-a disease characterized by ma...
The detection of circulating molecular biomarkers is useful for monitoring pathogenic processes and response to therapeutic intervention1,2. In cancer, genomic and proteomic biomarkers are us...
Acral lentiginous melanoma (ALM) is a rare sun-shielded melanoma subtype associated with worse survival than cutaneous melanoma (CM), a more common form of skin cancer linked to exposure to u...
We developed two computational methods, CARE and TIDE, to predict response and resistance to targeted therapies and immunotherapies. CARE infers gene signatures of targeted therapy response b...
Pancreatic cancer is one of the “deadly” cancers, defined as those with a 5-year relative survival rate of less than 50%. Although ranking 12th in terms of incidence, it is...
Nanopore sequencing has enormous potential for application to cancer, but specifically offers advantages into two main arenas, epigenetics and structural variation. Methylation is well-known...
There has been a great deal of renewed attention in immuno-oncology over the last decade. Therapies for cancer are being developed, approved, and administered that can either initiate,...
DATE: October 10, 2017TIME: 7:00 AM PT, 10:00 AM ETQuality assessment of monoclonal antibodies can be a bottleneck in biopharmaceutical workflows because of the complexity and length of...
Traditional high throughput screening (HTS) assays for neuronal targets employ non-human primary neuronal cells due to the scale necessary for HTS. Isolation of mouse primary neurons can be u...
The Resource Identification Initiative supports NIH's new guidelines for Rigor and Transparency as these apply in biomedical publications. Authors are instructed to authenticate key biolo...
Stem cells can self-renew and differentiate into multiple different cell types. Engineering of stem cells has enabled new methods to study development and organogenesis in humans as well as d...
I will present my lab’s effort on studying and manipulating RNA processing, with particular emphasis on using CRISPR/Cas systems for targeting RNA in living cells in diseases such as my...
The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
DATE: September 20, 2017TIME: 11:30AM PDTCoffea arabica accounts for 70% of world coffee production and is threatened by various biotic and abiotic factors. In this webinar, Dr. Susan S...
Genome sequencing can be used to discover new pathogens but it can also be used to monitor known ones. This is known as genomic surveillance and it becoming an increasingly important tool in...
Quinolones are one the most commonly prescribed classes of antibacterials in the world and are used to treat a broad variety of Gram-negative and Gram-positive bacterial infections in humans....
A rapidly growing number of viruses of lower eukaryotes have been reported in the past few decades. These have enhanced our understanding of virus evolution and diversity. Simultaneously, som...
Background: In March 2014, a molecular cluster of five multidrug resistant Mycobacterium tuberculosis was detected by the Austrian National Reference Laboratory. An investigation was initiate...
Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
Increasing prevalence and severity of multi-drug-resistant (MDR) bacterial infections has necessitated novel antibacterial strategies. Ideally, new approaches would target bacterial pat...
Prokaryotes have long been at war with bacteriophage. The evolutionary pressure of this struggle has led both sides to develop sophisticated defenses. Notably, CRISPR-Cas systems evolved to l...
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