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    Gene Expression

    Gene Expression: the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA. The process of gene expression is used by all known life-eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses-to generate the macromolecular machinery for life.

    Webinars

    • SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      In vivo delivery of Cas9 ribonucleoprotein and donor DNA with gold nanoparticles
      In vivo delivery of Cas9 ribonucleoprotein and donor DNA with...
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy
      Presented at: CRISPR Virtual Event Series 2020
      4
      SEP 30, 2020 | 12:00 AM
      An Automated Integrated Multiple Assay Platform utilizing CRISPR-based Transistors for CRISPR Quality Control Applications
      An Automated Integrated Multiple Assay Platform utilizing CRISPR-based...
      Learning Objectives: 1. Using an optics- and label-free approach to CRISPR research 2. Explain current approaches to selecting the most robust gRNA for CRISPR assays 3. The opportunities tha...
      Speaker: Kiana Aran, PhD
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 30, 2020 | 12:00 AM
      Applying targeted long-read sequencing to assess an expanded repeat in C9orf72
      Applying targeted long-read sequencing to assess an expanded repeat...
      A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
      Speaker: Marka van Blitterswijk, MD, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
      An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
      Speaker: Adam Ameur
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 23, 2020 | 7:30 AM
      Cell Culture Troubleshooting Tips and Tricks
      Cell Culture Troubleshooting Tips and Tricks
      Cell culture continues to be a critical tool for most life science research and applications. From HeLa to iPSCs and 3D to organoids, culture methods have become more advanced and techniques...
      Speaker: Marina Wiklander, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      6
      SEP 23, 2020 | 12:00 AM
      Transcriptomic signature : a spatially resolved analysis of the nephron structures in chronic kidney disease
      Transcriptomic signature : a spatially resolved analysis of the...
      Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for...
      Speaker: Paolo Cravedi, MD, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      2
      SEP 23, 2020 | 12:00 AM
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
      GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
      Speaker: Kit Fuhrman
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 17, 2020 | 12:00 PM
      Advanced NGS solutions for SARS-CoV-2 monitoring and insights
      Advanced NGS solutions for SARS-CoV-2 monitoring and insights
      Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development, detect emerging viral strains and monitor transmission patterns. Enhanced...
      Speaker: Cris Kinross
      Presented at: Coronavirus Series
      Sponsored By: Thermo Fisher Scientific
      1
      SEP 17, 2020 | 9:00 AM
      Preclinical Optical Imaging of Infectious Diseases
      Preclinical Optical Imaging of Infectious Diseases
      PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
      Speaker: Kevin Francis, PhD
      Presented at: Coronavirus Series
      Sponsored By: PerkinElmer
      1
      SEP 16, 2020 | 12:45 PM
      GFP Complementation Screening of the Yeast Inner Nuclear Membrane Proteome
      GFP Complementation Screening of the Yeast Inner Nuclear Membrane...
      The inner nuclear membrane of eukaryotic cells defines many aspects of gene expression and chromatin organization. It is also therapeutically important as several diseases, termed “lam...
      Speaker: Jay Unruh, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      1
      SEP 16, 2020 | 12:15 PM
      High-resolution HCA-based phenotypic profiling of tumor spheroids and organoids
      High-resolution HCA-based phenotypic profiling of tumor spheroids...
      Image-based high-content screening (HCS) involving cancer cell lines grown in conventional two-dimensional (2D) cell culture, has provided a cornerstone assay for searching new agents to tre...
      Speaker: Meritxell B. Cutrona, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      2
      SEP 16, 2020 | 9:00 AM
      Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
      Deep multi-omic phenotyping of biospecimens for immuno-oncology...
      Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
      Speaker: Dr. Shawn Fahl
      Sponsored By: Miltenyi Biotec
      11
      SEP 10, 2020 | 2:00 PM
      Dynamic live yeast and bacterial cell imaging using CellASIC ONIX2 microfluidic platform
      Dynamic live yeast and bacterial cell imaging using CellASIC ONIX2...
      While live cell imaging offers advantages over traditional static imaging, this approach has been challenging for studying microbes due to the difficulty in tracking very small cells in a si...
      Speaker: Cindy Chen, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      SEP 10, 2020 | 12:00 PM
      Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
      Bacterial strain typing and genomics characterization of multi-drug...
      In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
      Speaker: Jonathan Jacobs, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      SEP 09, 2020 | 12:00 AM
      Lung immune cells as drivers of influenza outcomes
      Lung immune cells as drivers of influenza outcomes
      Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
      Speaker: Juliet Morrison, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 09, 2020 | 12:00 AM
      Understanding the role of virus-host interactions in tissue tropism of plant viruses
      Understanding the role of virus-host interactions in tissue tropism...
      To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
      Speaker: Svetlana Y. Folimonova
      Presented at: Microbiology Week Virtual Event Series 2020
      2
      SEP 09, 2020 | 12:00 AM
      Bacterial Epigenomes: Technology, Pathogens and Microbiome
      Bacterial Epigenomes: Technology, Pathogens and Microbiome
      Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated resid...
      Speaker: Gang Fang
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 08, 2020 | 11:00 PM
      Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
      Deep mutational scanning of SARS-CoV-2 receptor binding domain...
      The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutraliz...
      Speaker: Tyler Starr, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      SEP 08, 2020 | 9:00 AM
      Advancing Toward Personalized Medicine in Lung Cancer: A Focus on Gene Rearrangement Testing
      Advancing Toward Personalized Medicine in Lung Cancer: A Focus...
      Advances in genomics and molecular biomarker testing have led to tremendous improvements, ushering in a new era of personalized medicine especially in the oncology practice. Many of these bi...
      Speaker: Yelina Noskina, PhD
      Sponsored By: Scientific Affairs, Molecular Diagnostics at Abbott
      27 3
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 25, 2020 | 8:00 AM
      How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
      How LV and AAV Transfection Platforms will Shape the Future of...
      DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
      Speaker: Leisha Kopp
      Sponsored By: Mirus
      18 2
      AUG 18, 2020 | 10:00 AM
      Visualize ASO, miRNA, and siRNA Detections with Spatial Resolution using the New miRNAscope™ Assay
      Visualize ASO, miRNA, and siRNA Detections with Spatial Resolution...
      DATE: August 18, 2020 TIME: 10:00am PT Get deeper understanding of gene expression patterns by using assays that retain spatial organization at single cell resolution! Come learn about the n...
      Speaker: Helly Pimentel , Miguel Mata
      Sponsored By: Advanced Cell Diagnostics
      26 2
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 30, 2020 | 12:00 AM
    In vivo delivery of Cas9 ribonucleoprotein and donor DNA with gold nanoparticles
    In vivo delivery of Cas9 ribonucleoprotein and donor DNA with...
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy
    Presented at: CRISPR Virtual Event Series 2020
    4
    SEP 30, 2020 | 12:00 AM
    An Automated Integrated Multiple Assay Platform utilizing CRISPR-based Transistors for CRISPR Quality Control Applications
    An Automated Integrated Multiple Assay Platform utilizing CRISPR-based...
    Learning Objectives: 1. Using an optics- and label-free approach to CRISPR research 2. Explain current approaches to selecting the most robust gRNA for CRISPR assays 3. The opportunities tha...
    Speaker: Kiana Aran, PhD
    Presented at: CRISPR Virtual Event Series 2020
    1
    SEP 30, 2020 | 12:00 AM
    Applying targeted long-read sequencing to assess an expanded repeat in C9orf72
    Applying targeted long-read sequencing to assess an expanded repeat...
    A repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) represents the most common genetic cause of two fatal neurodegenerative diseases: frontotemporal dementia (FTD) and amyotrop...
    Speaker: Marka van Blitterswijk, MD, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 30, 2020 | 12:00 AM
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    Long-read sequencing reveals unforeseen CRISPR-Cas9 activity
    An extensively debated concern about CRISPR-Cas9 genome editing is that unspecific guide RNA (gRNA) binding may induce off-target mutations. However, accurate prediction of CRISPR-Cas9 off-t...
    Speaker: Adam Ameur
    Presented at: CRISPR Virtual Event Series 2020
    1
     
     
  • SEP 23, 2020 | 7:30 AM
    Cell Culture Troubleshooting Tips and Tricks
    Cell Culture Troubleshooting Tips and Tricks
    Cell culture continues to be a critical tool for most life science research and applications. From HeLa to iPSCs and 3D to organoids, culture methods have become more advanced and techniques...
    Speaker: Marina Wiklander, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    6
    SEP 23, 2020 | 12:00 AM
    Transcriptomic signature : a spatially resolved analysis of the nephron structures in chronic kidney disease
    Transcriptomic signature : a spatially resolved analysis of the...
    Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for...
    Speaker: Paolo Cravedi, MD, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    2
    SEP 23, 2020 | 12:00 AM
    GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
    GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
    GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
    Speaker: Kit Fuhrman
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 17, 2020 | 12:00 PM
    Advanced NGS solutions for SARS-CoV-2 monitoring and insights
    Advanced NGS solutions for SARS-CoV-2 monitoring and insights
    Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development, detect emerging viral strains and monitor transmission patterns. Enhanced...
    Speaker: Cris Kinross
    Presented at: Coronavirus Series
    Sponsored By: Thermo Fisher Scientific
    1
    SEP 17, 2020 | 9:00 AM
    Preclinical Optical Imaging of Infectious Diseases
    Preclinical Optical Imaging of Infectious Diseases
    PerkinElmer is a global leader in the development of instrumentation and probes for small animal non-invasive imaging, including optical and µCT imaging. Through optical imaging, we ha...
    Speaker: Kevin Francis, PhD
    Presented at: Coronavirus Series
    Sponsored By: PerkinElmer
    1
     
     
  • SEP 16, 2020 | 12:45 PM
    GFP Complementation Screening of the Yeast Inner Nuclear Membrane Proteome
    GFP Complementation Screening of the Yeast Inner Nuclear Membrane...
    The inner nuclear membrane of eukaryotic cells defines many aspects of gene expression and chromatin organization. It is also therapeutically important as several diseases, termed “lam...
    Speaker: Jay Unruh, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    1
    SEP 16, 2020 | 12:15 PM
    High-resolution HCA-based phenotypic profiling of tumor spheroids and organoids
    High-resolution HCA-based phenotypic profiling of tumor spheroids...
    Image-based high-content screening (HCS) involving cancer cell lines grown in conventional two-dimensional (2D) cell culture, has provided a cornerstone assay for searching new agents to tre...
    Speaker: Meritxell B. Cutrona, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    2
    SEP 16, 2020 | 9:00 AM
    Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
    Deep multi-omic phenotyping of biospecimens for immuno-oncology...
    Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
    Speaker: Dr. Shawn Fahl
    Sponsored By: Miltenyi Biotec
    11
    SEP 10, 2020 | 2:00 PM
    Dynamic live yeast and bacterial cell imaging using CellASIC ONIX2 microfluidic platform
    Dynamic live yeast and bacterial cell imaging using CellASIC ONIX2...
    While live cell imaging offers advantages over traditional static imaging, this approach has been challenging for studying microbes due to the difficulty in tracking very small cells in a si...
    Speaker: Cindy Chen, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
    SEP 10, 2020 | 12:00 PM
    Bacterial strain typing and genomics characterization of multi-drug resistance with QIAGEN CLC Genomics Workbench
    Bacterial strain typing and genomics characterization of multi-drug...
    In this webinar, we will present QIAGEN CLC Genomics Workbench and its utility for bacterial isolate identification, strain discrimination using core genome multi-locus typing (cgMLST) and d...
    Speaker: Jonathan Jacobs, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
     
     
  • SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    SEP 09, 2020 | 12:00 AM
    Lung immune cells as drivers of influenza outcomes
    Lung immune cells as drivers of influenza outcomes
    Influenza severity is determined by the interplay between the virus and the host response. Previously, we identified a three-pronged lung gene expression signature that predicted severe infl...
    Speaker: Juliet Morrison, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 09, 2020 | 12:00 AM
    Understanding the role of virus-host interactions in tissue tropism of plant viruses
    Understanding the role of virus-host interactions in tissue tropism...
    To establish productive infection, plant viruses need to be able to efficiently invade and spread within a plant. Most viruses are introduced into a plant via the epidermal or mesophyll cell...
    Speaker: Svetlana Y. Folimonova
    Presented at: Microbiology Week Virtual Event Series 2020
    2
    SEP 09, 2020 | 12:00 AM
    Bacterial Epigenomes: Technology, Pathogens and Microbiome
    Bacterial Epigenomes: Technology, Pathogens and Microbiome
    Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated resid...
    Speaker: Gang Fang
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    SEP 08, 2020 | 11:00 PM
    Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
    Deep mutational scanning of SARS-CoV-2 receptor binding domain...
    The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor, and is a major determinant of host range and a dominant target of neutraliz...
    Speaker: Tyler Starr, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    4
     
     
  • SEP 08, 2020 | 9:00 AM
    Advancing Toward Personalized Medicine in Lung Cancer: A Focus on Gene Rearrangement Testing
    Advancing Toward Personalized Medicine in Lung Cancer: A Focus...
    Advances in genomics and molecular biomarker testing have led to tremendous improvements, ushering in a new era of personalized medicine especially in the oncology practice. Many of these bi...
    Speaker: Yelina Noskina, PhD
    Sponsored By: Scientific Affairs, Molecular Diagnostics at Abbott
    27 3
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
    AUG 25, 2020 | 8:00 AM
    How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
    How LV and AAV Transfection Platforms will Shape the Future of...
    DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
    Speaker: Leisha Kopp
    Sponsored By: Mirus
    18 2
    AUG 18, 2020 | 10:00 AM
    Visualize ASO, miRNA, and siRNA Detections with Spatial Resolution using the New miRNAscope™ Assay
    Visualize ASO, miRNA, and siRNA Detections with Spatial Resolution...
    DATE: August 18, 2020 TIME: 10:00am PT Get deeper understanding of gene expression patterns by using assays that retain spatial organization at single cell resolution! Come learn about the n...
    Speaker: Helly Pimentel , Miguel Mata
    Sponsored By: Advanced Cell Diagnostics
    26 2
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