With the goal of treating and curing disease, gene and cell therapy provide treatment by means of altering a person's genetic code and transferring live cells to improve symptoms and reduce levels of disease-causing proteins.
Psychiatric disorders are among the leading causes of disability worldwide. One fifth of the population will suffer from a psychiatric disorder in their lifetime. Antipsychotic and antidepres...
Liquid Biopsies are gaining acceptance in the Oncology community as a surrogate or complement to the gold standard of tissue biopsy. A liquid biopsy provides biomarker information that...
Best practices for developing precision medicine diagnostics can include completing a retrospective analysis. Obtaining enough samples to have a statistically significant study typicall...
Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
Challenges in achieving comparability, reproducibility and accuracy in biological assays has driven a demand for improved confidence in measurements that support development of regenerative m...
In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease. While there is a scientific basis...
Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETMeloxicam is an analgesic NSAID commonly used in mice. Anecdotal evidence supports the use of alternative delivery methods for analgesics...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
Stem cells play critical roles in the development of organisms, as well as in the maintenance and repair of organs and tissues throughout adulthood. Advancing our understanding of mecha...
This panel will discuss quality requirements of ancillary materials used in cell therapy manufacturing, relevant standards and how requirements vary by phase. Participants will learn wh...
DATE: November 17, 2016
TIME: 7:00am PT, 10:00am ET
Induced pluripotent stem (iPS) cell reprogramming allows turning an adult somatic cell into a pluripotent stem cell. Four Fac...
The Alliance for Regenerative Medicine (ARM) is the preeminent global advocate for regenerative and advanced therapies. ARM fosters research, development, investment and commercialization of ...
Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance. This adaptive immunity can be reversed to stimulate the endogenous immune re...
PRESENTED BY:DATE: September 29, 2016TIME: 8:00AM PT, 11AM ETInterest in 3D cell culture has grown exponentially in recent years, partially due to 3D cultures hel...
PrPC is a conserved lipid-raft associated, GPI-anchored cell membrane glycoprotein. Misfolding of cellular PrPC into the pathogenic PrPSc results in Prion disease, an untreatable and fatal ne...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
Psychiatric disorders are among the leading causes of disability worldwide. One fifth of the population will suffer from a psychiatric disorder in their lifetime. Antipsychotic and antidepres...
Liquid Biopsies are gaining acceptance in the Oncology community as a surrogate or complement to the gold standard of tissue biopsy. A liquid biopsy provides biomarker information that...
Best practices for developing precision medicine diagnostics can include completing a retrospective analysis. Obtaining enough samples to have a statistically significant study typicall...
Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
Challenges in achieving comparability, reproducibility and accuracy in biological assays has driven a demand for improved confidence in measurements that support development of regenerative m...
In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease. While there is a scientific basis...
Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETMeloxicam is an analgesic NSAID commonly used in mice. Anecdotal evidence supports the use of alternative delivery methods for analgesics...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
Stem cells play critical roles in the development of organisms, as well as in the maintenance and repair of organs and tissues throughout adulthood. Advancing our understanding of mecha...
This panel will discuss quality requirements of ancillary materials used in cell therapy manufacturing, relevant standards and how requirements vary by phase. Participants will learn wh...
DATE: November 17, 2016
TIME: 7:00am PT, 10:00am ET
Induced pluripotent stem (iPS) cell reprogramming allows turning an adult somatic cell into a pluripotent stem cell. Four Fac...
The Alliance for Regenerative Medicine (ARM) is the preeminent global advocate for regenerative and advanced therapies. ARM fosters research, development, investment and commercialization of ...
Tumors often evade immune destruction by adapting and circumventing immune checkpoints to create resistance. This adaptive immunity can be reversed to stimulate the endogenous immune re...
PRESENTED BY:DATE: September 29, 2016TIME: 8:00AM PT, 11AM ETInterest in 3D cell culture has grown exponentially in recent years, partially due to 3D cultures hel...
PrPC is a conserved lipid-raft associated, GPI-anchored cell membrane glycoprotein. Misfolding of cellular PrPC into the pathogenic PrPSc results in Prion disease, an untreatable and fatal ne...
A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
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