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Functional Genomics
A field of genomics that utilizes the data from transcriptomic and genomic projects in order to study the more dynamic aspects of the genetic processes. This includes processes such as transcription, translation, and other epigenetic paths, while not focusing on the more static aspects such as secondary structure or sequences.
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APR 15, 2021 | 7:00 AM
Date: April 15, 2021 Time: 7:00am (PDT), 10:00am (EDT) In widefield fluorescence microscopy both the contrast and resolution of a captured image is corrupted by light collected from adjacent...FEB 24, 2021 | 7:00 AM
Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...FEB 03, 2021 | 12:30 PM
In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...JAN 26, 2021 | 8:00 AM
Date: January 26, 2021 Time: 9:00am (PST), 12:00pm (EST) Over the past years, CRISPR/Cas genome editing has quickly become the method of choice for genetic manipulation, owing to its ease-of...DEC 03, 2020 | 4:30 PM
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...NOV 19, 2020 | 9:00 AM
Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...NOV 16, 2020 | 8:00 AM
Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...OCT 29, 2020 | 8:00 AM
Date: October 29, 2020 Time: 8:00am (PDT), 11:00am (EDT) What cell types cause and perpetuate disease? For many diseases, scientists only have guesses to this critical question. Single cell...OCT 29, 2020 | 6:00 AM
Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam CribbsSponsored By: Illumina, Dolomite BioOCT 22, 2020 | 7:40 AM
IIdentification of relevant mutations, determination of tumor mutational burden (TMB) and microsatellite (MS) status are paramount to precision oncology research and the Oncomine Comprehensi...OCT 22, 2020 | 7:40 AM
Identification of actionable mutations, determination of tumor mutational burden (TMB) and microsatellite (MS) status are paramount to precision oncology and the Oncomine Comprehensive Assay...OCT 13, 2020 | 2:30 PM
...Speaker: Arjun Khanna , David Chi Leung Lam, MD, PhD , Chein-Feng Li, MD , Darren Wan Teck LimOCT 08, 2020 | 3:00 PM
The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...Speaker: Benjamin Borgo, PhDOCT 08, 2020 | 9:00 AM
Date: October 8, 2020 Time: 9:00am (PTD), 12:00pm (EDT), 5:00pm (GMT) Small DNA viruses require both host DNA replication and repair factors for their replication. The host cell replication...OCT 08, 2020 | 7:30 AM
Individuals of under-represented minority ancestry are at disproportional risk for higher incidence and mortality rates for particular cancers. The unequal burden of cancer in certain racial...Speaker: Steven R. Patierno, PhDOCT 08, 2020 | 6:00 AM
Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...Speaker: Christian Regenbrecht, PhDPresented at: Cancer Research & Oncology Week Virtual Event Series 2020
Sponsored By: Luminex - A DiaSorin CompanyOCT 01, 2020 | 11:00 AM
Date: October 1, 2020 Time: 10:00am (PTD), 1:00pm (EDT) Cancer cells rely on altered metabolism to support their proliferation. We performed a CRISPR/Cas9 functional genomic screen targeting...SEP 30, 2020 | 1:30 PM
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhDPresented at: CRISPR Virtual Event Series 2020
SEP 30, 2020 | 10:30 AM
CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...Speaker: James Goldmeyer, PhDSEP 30, 2020 | 7:30 AM
Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...SEP 30, 2020 | 12:00 AM
Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...SEP 30, 2020 | 12:00 AM
Learning Objectives: 1. Using an optics- and label-free approach to CRISPR research 2. Explain current approaches to selecting the most robust gRNA for CRISPR assays 3. The opportunities tha...SEP 17, 2020 | 11:00 AM
In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...SEP 10, 2020 | 10:00 AM
Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...
APR 15, 2021 | 7:00 AM
Date: April 15, 2021 Time: 7:00am (PDT), 10:00am (EDT) In widefield fluorescence microscopy both the contrast and resolution of a captured image is corrupted by light collected from adjacent...
FEB 24, 2021 | 7:00 AM
Date: February 24, 2021 Time: 7:00am (PST) Nucleotide variants can cause functional changes by altering protein–RNA binding in various ways that are not easy to predict. This can affec...
FEB 03, 2021 | 12:30 PM
In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
JAN 26, 2021 | 8:00 AM
Date: January 26, 2021 Time: 9:00am (PST), 12:00pm (EST) Over the past years, CRISPR/Cas genome editing has quickly become the method of choice for genetic manipulation, owing to its ease-of...
DEC 03, 2020 | 4:30 PM
This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
NOV 19, 2020 | 9:00 AM
Date: November 19, 2020 Time: 12:00am (PDT), 9:00am (CET), 4:00pm (SGT) We present split-FISH, a multiplexed fluorescence in situ hybridization method that leverages a split-probe design to...
NOV 16, 2020 | 8:00 AM
Date: November 16, 2020 Time: 8:00am (PST), 11:00am (EST) CRISPR screening has become the prime discovery tool in modern biomedical research and drug discovery. At the same time, most screen...
OCT 29, 2020 | 8:00 AM
Date: October 29, 2020 Time: 8:00am (PDT), 11:00am (EDT) What cell types cause and perpetuate disease? For many diseases, scientists only have guesses to this critical question. Single cell...
OCT 29, 2020 | 6:00 AM
Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
Speaker:
Thomas Ayers, Ph.D.
, Pawel Zajac, Ph.D.
, Dr. Adam Cribbs
Sponsored By: Illumina,
Dolomite Bio
OCT 22, 2020 | 7:40 AM
IIdentification of relevant mutations, determination of tumor mutational burden (TMB) and microsatellite (MS) status are paramount to precision oncology research and the Oncomine Comprehensi...
OCT 22, 2020 | 7:40 AM
Identification of actionable mutations, determination of tumor mutational burden (TMB) and microsatellite (MS) status are paramount to precision oncology and the Oncomine Comprehensive Assay...
OCT 13, 2020 | 2:30 PM
...
Speaker:
Arjun Khanna
, David Chi Leung Lam, MD, PhD
, Chein-Feng Li, MD
, Darren Wan Teck Lim
OCT 08, 2020 | 3:00 PM
The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
Speaker:
Benjamin Borgo, PhD
OCT 08, 2020 | 9:00 AM
Date: October 8, 2020 Time: 9:00am (PTD), 12:00pm (EDT), 5:00pm (GMT) Small DNA viruses require both host DNA replication and repair factors for their replication. The host cell replication...
OCT 08, 2020 | 7:30 AM
Individuals of under-represented minority ancestry are at disproportional risk for higher incidence and mortality rates for particular cancers. The unequal burden of cancer in certain racial...
Speaker:
Steven R. Patierno, PhD
OCT 08, 2020 | 6:00 AM
Every patient is different and so is every tumor! The term “personalized oncology” today is largely associated with sequencing approaches. Current publications proof more and mor...
Speaker:
Christian Regenbrecht, PhD
Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
Sponsored By: Luminex - A DiaSorin Company
Sponsored By: Luminex - A DiaSorin Company
OCT 01, 2020 | 11:00 AM
Date: October 1, 2020 Time: 10:00am (PTD), 1:00pm (EDT) Cancer cells rely on altered metabolism to support their proliferation. We performed a CRISPR/Cas9 functional genomic screen targeting...
SEP 30, 2020 | 1:30 PM
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 can be engineered for...
Speaker:
Omar Abudayyeh, PhD
, Jonathan Gootenberg, PhD
Presented at: CRISPR Virtual Event Series 2020
SEP 30, 2020 | 10:30 AM
CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
Speaker:
James Goldmeyer, PhD
SEP 30, 2020 | 7:30 AM
Genome Engineering allows the easy manipulation of genomes down to the nucleotide level. Targeted deep sequencing enables the detection and quantification of low-frequency editing events. Ho...
SEP 30, 2020 | 12:00 AM
Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
SEP 30, 2020 | 12:00 AM
Learning Objectives: 1. Using an optics- and label-free approach to CRISPR research 2. Explain current approaches to selecting the most robust gRNA for CRISPR assays 3. The opportunities tha...
SEP 17, 2020 | 11:00 AM
In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
SEP 10, 2020 | 10:00 AM
Enigmatic and often vilified, viruses are now known to play important and possibly indispensable roles in the biology and ecology of cellular organisms. Evidence of viral impacts are everywh...