DNA Methylation: an epigenetic mechanism used by cells to control gene expression. A number of mechanisms exist to control gene expression in eukaryotes, but DNA methylation is a commonly used epigenetic signaling tool that can fix genes in the "off" position.
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Epigenetics refers to the study of nuclear architecture and gene regulation. Epigenetic mechanisms govern many physiological processes such as cell differentiation, x-inactivation, and genomi...
Miniaturized microscopes in combination with genetically encoded calcium indicators now allow recordings of activity from hundreds of neurons simultaneously in freely moving animals. We are b...
Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
Mesenchymal stromal cell (MSC) therapy is a promising option to support endogenous regeneration and immunomodulation. However, the clinical results are contradictory. We think that the recent...
DNA methylation is an essential mechanism of epigenetic gene regulation with broad relevance in development and disease. Its localization on genomic DNA and general stability make this epigen...