Complex Systems is a journal devoted to the science, mathematics and engineering of systems with simple components but complex overall behavior. It is concerned with identifying and characterizing common design elements that are observed across diverse natural, technological and social complex systems.
Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
Molecular profiling is key in precision oncology research and whilst the tissue testing has become a routine, liquid biopsy might provide a non-invasive alternative when tissue biopsy is ina...
The development of molecular targeted therapy is one of the breakthroughs in oncology field. Molecular profiling of the tumor becomes mandatory in the routine clinical practice to select the...
Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
Approximately 300,000 people in the United States have a spinal cord injury with many of these individuals experiencing permanent motor and sensory deficits. For individuals with cervical sp...
Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
Brain machine interfaces or neural prosthetics have the potential to restore movement to people with paralysis or amputation, bridging gaps in the nervous system with an artificial device. M...
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
In Andalman et al, 2018, we explored the activity of over 10,000 neurons across more than 15 regions imaged simultaneously in larval zebrafish in a novel behavioral challenge paradigm. Compl...
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
DATE: November 13, 2019TIME: 8:00am PSTIn this presentation, Dr. Rizvi will outline the power and generality of single-cell studies, workflows enabling such studies, and skillful mean...
DATE: November 12, 2019TIME: 10:00am PSTDirect measurement of copy number by droplet-based shallow sequencing of genomic DNA has the potential to provide new insights into tumor heterog...
DATE: November 7, 2019TIME: 10:00am PST, 1:00pm EST Studying the pathogenesis of diabetes requires detailed analysis of the pancreatic islet microenvironment and its numerous c...
Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
DATE: October 29, 2019TIME: 8:00am PDTAlthough immune-based therapies targeting the inhibitory receptors (PD-L1, PD1, and CTLA4) are proven to be effective to treat cancer, some pati...
Chromatography is the first choice in separation technique for a wide selection of applications, across many fields, ranging from simple to highly complex extracts. The main rationale for it...
Accumulation of structural variations (SVs) across the genome is a known trigger factor for oncogenesis. Structural mutations have been clearly implicated in a number of cancers, most notably...
In this webinar, we will be discussing some of our most recent testing using our Cas9 proteins, Cas9 RNP nickases in a variety of human cell types, including primary T-cells. Cas nucleases wh...
Similar to the “histone code” hypothesis in which epigenetic marks on histone tails expand the information potential of the genetic code, different tubulin isoforms, combined wit...
Molecular profiling is key in precision oncology research and whilst the tissue testing has become a routine, liquid biopsy might provide a non-invasive alternative when tissue biopsy is ina...
The development of molecular targeted therapy is one of the breakthroughs in oncology field. Molecular profiling of the tumor becomes mandatory in the routine clinical practice to select the...
Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
Approximately 300,000 people in the United States have a spinal cord injury with many of these individuals experiencing permanent motor and sensory deficits. For individuals with cervical sp...
Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
Brain machine interfaces or neural prosthetics have the potential to restore movement to people with paralysis or amputation, bridging gaps in the nervous system with an artificial device. M...
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
In Andalman et al, 2018, we explored the activity of over 10,000 neurons across more than 15 regions imaged simultaneously in larval zebrafish in a novel behavioral challenge paradigm. Compl...
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
DATE: November 13, 2019TIME: 8:00am PSTIn this presentation, Dr. Rizvi will outline the power and generality of single-cell studies, workflows enabling such studies, and skillful mean...
DATE: November 12, 2019TIME: 10:00am PSTDirect measurement of copy number by droplet-based shallow sequencing of genomic DNA has the potential to provide new insights into tumor heterog...
DATE: November 7, 2019TIME: 10:00am PST, 1:00pm EST Studying the pathogenesis of diabetes requires detailed analysis of the pancreatic islet microenvironment and its numerous c...
Multiple factors can affect and impact infection dynamics and virulence produced by influenza virus (IV) infections. Susceptibility factors and host responses can also have major effects in d...
DATE: October 29, 2019TIME: 8:00am PDTAlthough immune-based therapies targeting the inhibitory receptors (PD-L1, PD1, and CTLA4) are proven to be effective to treat cancer, some pati...
Chromatography is the first choice in separation technique for a wide selection of applications, across many fields, ranging from simple to highly complex extracts. The main rationale for it...
Accumulation of structural variations (SVs) across the genome is a known trigger factor for oncogenesis. Structural mutations have been clearly implicated in a number of cancers, most notably...
In this webinar, we will be discussing some of our most recent testing using our Cas9 proteins, Cas9 RNP nickases in a variety of human cell types, including primary T-cells. Cas nucleases wh...