Cells carry out specialized functions throughout the body and each cell type functions distinctly from other cell types. Some cellular functions include transporting nutrients throughout the body and producing energy. One specialized cell is muscle cells which function to create a force that moves parts of the body. Another example are bone cells, whose functions include protecting internal organs from damage and storing minerals such as calcium.
Antibody drug conjugates (ADCs) represent a novel method to deliver a drug to diseased cell using the specific antigen-binding capability and internalization process. Antibodies that do not i...
DATE: March 21, 2018TIME: 8:00AM PST, 11:00AM ESTMass cytometry, or cytometry by time-of-flight (the basis of the CyTOF® system), enables quantification of the abundance and fu...
How does a low-level sensory representation rise into conscious awareness? What determines whether higher-order cortical areas have access to the representational content in sensory regions?...
Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis. Even with such powerful technology at hand, sophisticated projects, su...
Most neuropsychiatric diseases involve multifactorial systems characterized by complex interactions among genetic predisposition/resiliency, environmental/social determinants, molecular seque...
The cerebellum is incorporated into the distributed neural circuits subserving motor control, cognitive processing and the modulation of emotion. This lecture provides an overview of anatomic...
Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
Preterm birth (PTB) is the leading cause of infant mortality and morbidity worldwide. Both preterm labor and neonatal injuries have been linked to inflammation. Of all mediators of inflammati...
The distinction between "complementary" and "companion" diagnostics tests confuse many physicians and healthcare professionals. Panelists Professor Thomas Webster (Northea...
One-third of FDA-approved drugs target G protein-coupled receptors (GPCRs), transmembrane cell surface proteins that recognize small molecules and polypeptides with diverse chemical scaffolds...
Most cell cycle assays amount to counting cells and/or measuring DNA content and deconvolving the resulting histogram into G1, S, G2+M, or G1, S, G2, and M. Considerable effort has been...
One of the goals of the “3Rs principle” is to replace in vivo testing methodologies with in vitro procedures on human cells, followed by computational systems biology modelling to...
DATE: January 30, 2018TIME: 9:00AM PST, 12:00PM ESTInfectious disease surveillance and monitoring is critical in settings where disease outbreaks and antibiotic resistance can dramatica...
DATE: January 25, 2018TIME: 8:00AM PST, 10:00AM CSTProstate cancer (PCa) is the most common noncutaneous malignancy in men in the US. A significant fraction of advanced PCa treate...
The capacity to generate disease-relevant cell populations from human pluripotent stem cells has tremendous potential for shedding light on human disease mechanisms. I will discuss basic prin...
My talk shall encompass how the stem cell research field has evolved from embryonic stem cells to adult stem cells and currently induced pluripotent stem cells with special reference to the f...
DATE: December 14, 2017TIME: 05:00am PST, 08:00am EST, 2:00pm CETvon Willebrand Disease (vWD) is one of the most common congenital bleeding disorders, affecting ~1%* of the world’...
DATE: December 12, 2017TIME: 10:00AM PTSince their discovery, dendritic cells (DCs) have demonstrated a central role in the development of effective immune responses. Their unique abili...
DATE: November 29, 2017TIME: 10:00 AM PSTThe three human RAS genes (HRAS, KRAS and NRAS) encode four highly related RAS small GTPases (HRAS, KRAS4A, KRAS4B and NRAS). RAS proteins funct...
Antibody drug conjugates (ADCs) represent a novel method to deliver a drug to diseased cell using the specific antigen-binding capability and internalization process. Antibodies that do not i...
DATE: March 21, 2018TIME: 8:00AM PST, 11:00AM ESTMass cytometry, or cytometry by time-of-flight (the basis of the CyTOF® system), enables quantification of the abundance and fu...
How does a low-level sensory representation rise into conscious awareness? What determines whether higher-order cortical areas have access to the representational content in sensory regions?...
Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis. Even with such powerful technology at hand, sophisticated projects, su...
Most neuropsychiatric diseases involve multifactorial systems characterized by complex interactions among genetic predisposition/resiliency, environmental/social determinants, molecular seque...
The cerebellum is incorporated into the distributed neural circuits subserving motor control, cognitive processing and the modulation of emotion. This lecture provides an overview of anatomic...
Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
G-protein coupled receptors (GPCRs) represent the single largest class of druggable targets in the human genome. Of the 390 or so druggable and non-olfactory human GPCRs there exist many whic...
Preterm birth (PTB) is the leading cause of infant mortality and morbidity worldwide. Both preterm labor and neonatal injuries have been linked to inflammation. Of all mediators of inflammati...
The distinction between "complementary" and "companion" diagnostics tests confuse many physicians and healthcare professionals. Panelists Professor Thomas Webster (Northea...
One-third of FDA-approved drugs target G protein-coupled receptors (GPCRs), transmembrane cell surface proteins that recognize small molecules and polypeptides with diverse chemical scaffolds...
Most cell cycle assays amount to counting cells and/or measuring DNA content and deconvolving the resulting histogram into G1, S, G2+M, or G1, S, G2, and M. Considerable effort has been...
One of the goals of the “3Rs principle” is to replace in vivo testing methodologies with in vitro procedures on human cells, followed by computational systems biology modelling to...
DATE: January 30, 2018TIME: 9:00AM PST, 12:00PM ESTInfectious disease surveillance and monitoring is critical in settings where disease outbreaks and antibiotic resistance can dramatica...
DATE: January 25, 2018TIME: 8:00AM PST, 10:00AM CSTProstate cancer (PCa) is the most common noncutaneous malignancy in men in the US. A significant fraction of advanced PCa treate...
The capacity to generate disease-relevant cell populations from human pluripotent stem cells has tremendous potential for shedding light on human disease mechanisms. I will discuss basic prin...
My talk shall encompass how the stem cell research field has evolved from embryonic stem cells to adult stem cells and currently induced pluripotent stem cells with special reference to the f...
DATE: December 14, 2017TIME: 05:00am PST, 08:00am EST, 2:00pm CETvon Willebrand Disease (vWD) is one of the most common congenital bleeding disorders, affecting ~1%* of the world’...
DATE: December 12, 2017TIME: 10:00AM PTSince their discovery, dendritic cells (DCs) have demonstrated a central role in the development of effective immune responses. Their unique abili...
DATE: November 29, 2017TIME: 10:00 AM PSTThe three human RAS genes (HRAS, KRAS and NRAS) encode four highly related RAS small GTPases (HRAS, KRAS4A, KRAS4B and NRAS). RAS proteins funct...
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