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    Cancer Therapeutics

    Cancer Therapeutics: Cancer is often treated by surgery, chemotherapy, radiation therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy), hormonal therapy, and synthetic lethality. The choice of therapy depends upon the stage of the disease, and the location and grade of the tumor, as well as the patient's general status. Many clinical trial cancer treatments are also under development.

    Webinars

    • APR 07, 2016 | 9:00 AM
      The impact of precise medicine on the practice of classical pathology -- What are some of the challenges and opportunities?
      The impact of precise medicine on the practice of classical pathology...
      Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
      Speaker: Michael Donovan, MD, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      2
      APR 07, 2016 | 7:30 AM
      The Personalis ACE CancerPlus Test: A Comprehensive DNA & RNA Sequencing Solution for Guiding Clinical Care & Improving Patient Outcomes
      The Personalis ACE CancerPlus Test: A Comprehensive DNA & RNA...
      Oncologists and pathologists are increasingly utilizing information on genomic alterations in tumors to help guide patient care and treatment. Personalis, Inc., a genomic sequencing and inter...
      Speaker: Heather Wetzel, MS, LCGC
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      2
      APR 07, 2016 | 6:00 AM
      Ligand-Targeted Therapies for Cancer and Autoimmune Diseases
      Ligand-Targeted Therapies for Cancer and Autoimmune Diseases
      We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
      Speaker: Philip Low, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      2
      FEB 24, 2016 | 1:00 PM
      From genomics to precision medicine: Uncovering and manipulating the genetic circuits underlying common disease
      From genomics to precision medicine: Uncovering and manipulating...
      Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
      Speaker: Manolis Kellis, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 11:00 AM
      Precision Ferroptosis Inducers: Death by Lipid Peroxidation
      Precision Ferroptosis Inducers: Death by Lipid Peroxidation
      Cell death is involved in diseases such as cancer and neurodegeneration, and also has a natural role in the development of multicellular organisms. Although apoptosis has been well defined, a...
      Speaker: Brent Stockwell, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 10:00 AM
      Harnessing the Power of Healthcare Data with Causal Machine Learning to drive Personalized and Effective Treatment Interventions
      Harnessing the Power of Healthcare Data with Causal Machine Learning...
      Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
      Speaker: Iya Khalil, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 02, 2016 | 9:00 AM
      Arrays or RNA-Seq? Choosing the right tool for the job
      Arrays or RNA-Seq? Choosing the right tool for the job
      DATE: February 2nd, 2016 TIME:  9am pacific time, 12pm eastern time What is the most appropriate technology to empower your research?   Next generation sequencing (NGS) for RN...
      Speaker: Sridar Chittur, PhD, MBA , Yesim Gökmen-Polar, PhD
      Sponsored By: Affymetrix, Affymetrix
      11 3
      JAN 20, 2016 | 8:00 AM
      Extracellular Vesicle Detection and Analysis via Flow Cytometry
      Extracellular Vesicle Detection and Analysis via Flow Cytometry
      Over the past decade, there has been a rapid growth in studies of secreted membrane vesicles, collectively called extracellular vesicles (EVs). (1) The release of EVs has been reported in the...
      Speaker: Vasilis Toxavidis , John Tigges
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      7 2
      NOV 11, 2015 | 6:00 AM
      Clinical next-generation sequencing for precision cancer therapeutics
      Clinical next-generation sequencing for precision cancer therapeutics
      Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
      Speaker: Christina (Tina) Lockwood, PhD, DABCC, FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      2
      NOV 04, 2015 | 11:00 AM
      Advances in AMPK and Autophagy signaling
      Advances in AMPK and Autophagy signaling
      DATE: November 4th, 2015 TIME: 11:00am Pacific time, 2:00pm Eastern time AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
      Speaker: Reuben Shaw, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      14 1
      OCT 01, 2015 | 12:00 PM
      Can the World's First Animal Study Software to Emulate Clinical Trial Approaches Improve Clinical Outcome Predictability?
      Can the World's First Animal Study Software to Emulate Clinical...
      The 95% failure rate of anticancer therapeutic being approved after positive Phase III trials suggests that existing pre-clinical approaches and tools are inadequate predictors of clinical ou...
      Speaker: Eric Ibsen
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      3
      OCT 01, 2015 | 7:30 AM
      A Case Study for Immunotherapies and Targeted Therapies
      A Case Study for Immunotherapies and Targeted Therapies
      Melanoma, a cancer of pigment-producing cells, accounts for nearly 200,000 new cases of cancer reported each year worldwide. It is the deadliest skin cancer. Alarmingly, in the U.S., the inci...
      Speaker: Louise Perkins, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      OCT 01, 2015 | 7:30 AM
      Latest clinical results in oncology drug management
      Latest clinical results in oncology drug management
      While TDM is routinely used in a number of medical fields, it has not gained wide utilization in oncology. There is a growing body of evidence demonstrating that current dosing methods based...
      Speaker: Salvatore Salamone, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 1:30 PM
      Biomarkers: An Auspicious Beginning and a Portentous Future?
      Biomarkers: An Auspicious Beginning and a Portentous Future?
      Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...
      Speaker: Anna Barker, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 12:00 PM
      Modeling and dissecting hepatocellular carcinoma dissemination
      Modeling and dissecting hepatocellular carcinoma dissemination
      Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
      Speaker: Brian Lewis, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 9:00 AM
      Lactate-driven metabolic adaptation modulates breast cancer progression
      Lactate-driven metabolic adaptation modulates breast cancer progression
      The Warburg effect or aerobic glycolysis is a well-known cancer metabolism phenomenon and serves as an established test for tumor detection with FDG-PET scanning technology. Cancer cells swit...
      Speaker: Jennifer Molina, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 7:30 AM
      Ligand-Targeted Therapies for Cancer and Autoimmune Diseases
      Ligand-Targeted Therapies for Cancer and Autoimmune Diseases
      We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
      Speaker: Philip Low, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 7:30 AM
      How do I choose? Androgen Biosynthesis Inhibitor, Androgen Receptor Antagonist, or both for treatment of mCRPC?
      How do I choose? Androgen Biosynthesis Inhibitor, Androgen Receptor...
      The landscape for treatment options in metastatic castration resistant prostate cancer has changed dramatically since 2010. There have been more therapies approved since 2010 than in the prio...
      Speaker: Lawrence Karsh MD FACS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 6:00 AM
      Keynote Presentation: What's New and in the News with Prostate Cancer 2015
      Keynote Presentation: What's New and in the News with Prostate...
      LEARNING OBJECTIVES:1.    Enhanced audience understanding regarding the controversy surrounding prostate cancer screening using the PSA blood test and use of the American Uro...
      Speaker: Judd W Moul, MD, FACS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      4
      SEP 02, 2015 | 6:00 AM
      Structure and Function of the Human Microbiome
      Structure and Function of the Human Microbiome
      Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
      Speaker: Curtis Huttenhower, PhD
      Presented at: Microbiology Virtual Event Series 2015
      9
      SEP 02, 2015 | 6:00 AM
      Rapid Tests to Decipher Microbiome Function in Health and Disease
      Rapid Tests to Decipher Microbiome Function in Health and Disease
      Human microbiome projects have delivered our first glimpse into the microbial communities that reside in and on our bodies. Building on these efforts the research community has begun to corre...
      Speaker: Anisha Kharkia, MS
      Presented at: Microbiology Virtual Event Series 2015
      10
      JUN 17, 2015 | 8:00 AM
      Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
      Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
      DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
      Speaker: Mark Landers
      Sponsored By: Epic Sciences, Epic Sciences
      15 2
      MAY 14, 2015 | 1:30 PM
      Epigenomic Profiles of Asthma
      Epigenomic Profiles of Asthma
      Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
      Speaker: Ivana Yang, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      2
      MAY 14, 2015 | 1:30 PM
      Germline Cancer Genetics in 2015
      Germline Cancer Genetics in 2015
      Germline cancer genetics became a reality with the cloning of the tumor suppressor gene RB1 for hereditary retinoblastoma in 1986 by Friend and Weinberg. The existence of cancer susceptibili...
      Speaker: Judy E Garber, MD, MPH
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4
    APR 07, 2016 | 9:00 AM
    The impact of precise medicine on the practice of classical pathology -- What are some of the challenges and opportunities?
    The impact of precise medicine on the practice of classical pathology...
    Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
    Speaker: Michael Donovan, MD, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    2
    APR 07, 2016 | 7:30 AM
    The Personalis ACE CancerPlus Test: A Comprehensive DNA & RNA Sequencing Solution for Guiding Clinical Care & Improving Patient Outcomes
    The Personalis ACE CancerPlus Test: A Comprehensive DNA & RNA...
    Oncologists and pathologists are increasingly utilizing information on genomic alterations in tumors to help guide patient care and treatment. Personalis, Inc., a genomic sequencing and inter...
    Speaker: Heather Wetzel, MS, LCGC
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    2
    APR 07, 2016 | 6:00 AM
    Ligand-Targeted Therapies for Cancer and Autoimmune Diseases
    Ligand-Targeted Therapies for Cancer and Autoimmune Diseases
    We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
    Speaker: Philip Low, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    2
    FEB 24, 2016 | 1:00 PM
    From genomics to precision medicine: Uncovering and manipulating the genetic circuits underlying common disease
    From genomics to precision medicine: Uncovering and manipulating...
    Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
    Speaker: Manolis Kellis, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 24, 2016 | 11:00 AM
    Precision Ferroptosis Inducers: Death by Lipid Peroxidation
    Precision Ferroptosis Inducers: Death by Lipid Peroxidation
    Cell death is involved in diseases such as cancer and neurodegeneration, and also has a natural role in the development of multicellular organisms. Although apoptosis has been well defined, a...
    Speaker: Brent Stockwell, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
     
     
  • FEB 24, 2016 | 10:00 AM
    Harnessing the Power of Healthcare Data with Causal Machine Learning to drive Personalized and Effective Treatment Interventions
    Harnessing the Power of Healthcare Data with Causal Machine Learning...
    Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
    Speaker: Iya Khalil, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 02, 2016 | 9:00 AM
    Arrays or RNA-Seq? Choosing the right tool for the job
    Arrays or RNA-Seq? Choosing the right tool for the job
    DATE: February 2nd, 2016 TIME:  9am pacific time, 12pm eastern time What is the most appropriate technology to empower your research?   Next generation sequencing (NGS) for RN...
    Speaker: Sridar Chittur, PhD, MBA , Yesim Gökmen-Polar, PhD
    Sponsored By: Affymetrix, Affymetrix
    11 3
    JAN 20, 2016 | 8:00 AM
    Extracellular Vesicle Detection and Analysis via Flow Cytometry
    Extracellular Vesicle Detection and Analysis via Flow Cytometry
    Over the past decade, there has been a rapid growth in studies of secreted membrane vesicles, collectively called extracellular vesicles (EVs). (1) The release of EVs has been reported in the...
    Speaker: Vasilis Toxavidis , John Tigges
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    7 2
    NOV 11, 2015 | 6:00 AM
    Clinical next-generation sequencing for precision cancer therapeutics
    Clinical next-generation sequencing for precision cancer therapeutics
    Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
    Speaker: Christina (Tina) Lockwood, PhD, DABCC, FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    2
    NOV 04, 2015 | 11:00 AM
    Advances in AMPK and Autophagy signaling
    Advances in AMPK and Autophagy signaling
    DATE: November 4th, 2015 TIME: 11:00am Pacific time, 2:00pm Eastern time AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
    Speaker: Reuben Shaw, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    14 1
     
     
  • OCT 01, 2015 | 12:00 PM
    Can the World's First Animal Study Software to Emulate Clinical Trial Approaches Improve Clinical Outcome Predictability?
    Can the World's First Animal Study Software to Emulate Clinical...
    The 95% failure rate of anticancer therapeutic being approved after positive Phase III trials suggests that existing pre-clinical approaches and tools are inadequate predictors of clinical ou...
    Speaker: Eric Ibsen
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    3
    OCT 01, 2015 | 7:30 AM
    A Case Study for Immunotherapies and Targeted Therapies
    A Case Study for Immunotherapies and Targeted Therapies
    Melanoma, a cancer of pigment-producing cells, accounts for nearly 200,000 new cases of cancer reported each year worldwide. It is the deadliest skin cancer. Alarmingly, in the U.S., the inci...
    Speaker: Louise Perkins, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    OCT 01, 2015 | 7:30 AM
    Latest clinical results in oncology drug management
    Latest clinical results in oncology drug management
    While TDM is routinely used in a number of medical fields, it has not gained wide utilization in oncology. There is a growing body of evidence demonstrating that current dosing methods based...
    Speaker: Salvatore Salamone, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 1:30 PM
    Biomarkers: An Auspicious Beginning and a Portentous Future?
    Biomarkers: An Auspicious Beginning and a Portentous Future?
    Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...
    Speaker: Anna Barker, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 12:00 PM
    Modeling and dissecting hepatocellular carcinoma dissemination
    Modeling and dissecting hepatocellular carcinoma dissemination
    Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
    Speaker: Brian Lewis, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
     
     
  • SEP 30, 2015 | 9:00 AM
    Lactate-driven metabolic adaptation modulates breast cancer progression
    Lactate-driven metabolic adaptation modulates breast cancer progression
    The Warburg effect or aerobic glycolysis is a well-known cancer metabolism phenomenon and serves as an established test for tumor detection with FDG-PET scanning technology. Cancer cells swit...
    Speaker: Jennifer Molina, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 7:30 AM
    Ligand-Targeted Therapies for Cancer and Autoimmune Diseases
    Ligand-Targeted Therapies for Cancer and Autoimmune Diseases
    We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
    Speaker: Philip Low, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 7:30 AM
    How do I choose? Androgen Biosynthesis Inhibitor, Androgen Receptor Antagonist, or both for treatment of mCRPC?
    How do I choose? Androgen Biosynthesis Inhibitor, Androgen Receptor...
    The landscape for treatment options in metastatic castration resistant prostate cancer has changed dramatically since 2010. There have been more therapies approved since 2010 than in the prio...
    Speaker: Lawrence Karsh MD FACS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 6:00 AM
    Keynote Presentation: What's New and in the News with Prostate Cancer 2015
    Keynote Presentation: What's New and in the News with Prostate...
    LEARNING OBJECTIVES:1.    Enhanced audience understanding regarding the controversy surrounding prostate cancer screening using the PSA blood test and use of the American Uro...
    Speaker: Judd W Moul, MD, FACS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    4
    SEP 02, 2015 | 6:00 AM
    Structure and Function of the Human Microbiome
    Structure and Function of the Human Microbiome
    Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
    Speaker: Curtis Huttenhower, PhD
    Presented at: Microbiology Virtual Event Series 2015
    9
     
     
  • SEP 02, 2015 | 6:00 AM
    Rapid Tests to Decipher Microbiome Function in Health and Disease
    Rapid Tests to Decipher Microbiome Function in Health and Disease
    Human microbiome projects have delivered our first glimpse into the microbial communities that reside in and on our bodies. Building on these efforts the research community has begun to corre...
    Speaker: Anisha Kharkia, MS
    Presented at: Microbiology Virtual Event Series 2015
    10
    JUN 17, 2015 | 8:00 AM
    Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
    Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
    DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
    Speaker: Mark Landers
    Sponsored By: Epic Sciences, Epic Sciences
    15 2
    MAY 14, 2015 | 1:30 PM
    Epigenomic Profiles of Asthma
    Epigenomic Profiles of Asthma
    Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
    Speaker: Ivana Yang, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    2
    MAY 14, 2015 | 1:30 PM
    Germline Cancer Genetics in 2015
    Germline Cancer Genetics in 2015
    Germline cancer genetics became a reality with the cloning of the tumor suppressor gene RB1 for hereditary retinoblastoma in 1986 by Friend and Weinberg. The existence of cancer susceptibili...
    Speaker: Judy E Garber, MD, MPH
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4
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