Bioproduction is the production of biologics-based therapeutic drugs including protein-based therapeutics, vaccines, gene therapies as well as cell therapies; drugs so complex they can only be made in living systems or indeed are a living system (cell therapies).
-
Glycosylation is an important product quality attribute for biotherapeutic proteins expressed in CHO cells. Glycoform variability can significantly affect the safety and efficacy of therapeut...
Reliable autologous expression of recombinant human proteins - from gene sequence to the expressed and purified protein - in human or CHO cells is essential for many aspects of biomedical res...
HEK293和CHO细胞是快速、规模可调的悬浮培养系统中常用的细胞系,可用于瞬时蛋白表达。此次演讲介绍了瞬时表达的基本概念和使用材料,以及使用293或CHO细胞时需要考虑的主要差异。...
CHO cells are the predominant host for biotherapeutic protein expression, with roughly 70% of licensed biologics manufactured in CHO. Multiple attributes make CHO cells desirable for bi...
AUG 21, 2013 | 1:00 PM
C.E. CREDITS
Codon-optimization describes gene engineering approaches that use synonymous codon changes to increase protein production. It is used extensively for expressing recombinant protein drugs, gen...