Analytical research and development (AR&D) involves numerous processes required for drug development. AR&D includes processes such as reference standard qualification, validation of analytical methods, stability and degradation studies, and product testing.
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At Biogen Idec, we have implemented a 3 part innovation operating model which includes innovation mentoring, agile experimentation and transition of experiments into pilots. In this presenta...
At Biogen Idec, we have implemented a 3 part innovation operating model which includes innovation mentoring, agile experimentation and transition of experiments into pilots. In this presenta...
Colloidal nanoparticles have become important materials in biomedicine, catalysis, and optoelectronics. Their unique nanoscale properties stem from their size (particularly of the i...
The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
A recent publication in Nature Genetics1 analyzed TCGA data, and classified solid tumors into two mutually exclusive classes: C class tumors, driven by copy number alterations; and M class tu...
Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
Pharmcogenomics (PGx) is the 2nd potential clinical application of genomic medicine, preceded by genomic application for cancer. In the recently published, 2012 Institute of Medicine report o...