mouse monoclonal IgG2a; C/EBP β Antibody (H-7) is an IgG2a κ mouse monoclonal C/EBP beta antibody (also designated C/EBP beta antibody or CEBPB antibody) that detects the C/EBP beta protein of mouse, rat and human origin by WB, IP, IF and IHC(P). C/EBP β Antibody (H-7) is available as both the non-conjugated anti-C/EBP beta antibody form, as well as multiple conjugated forms of anti-C/EBP beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. CCAAT-enhancer binding proteins (C/EBP) are basic region/leucine zipper (bZIP) transcription factors selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP β is a member of the C/EBP transcription factor family. The C/EBP β gene encodes several isoforms containing truncated transcription activation domains due to the alternative translational initiation at multipe AUG start sites. C/EBP β is also known as interleukin 6-dependent DNA-binding protein (IL6DBP), liver activator protein (LAP) or liver-enriched transcriptional activator protein transcription factor 5 (TCF5). C/EBP β contributes to the regulation of the acute phase response in hepatocytes. Stat3 has an important function in IL-6-mediated transcription of the C/EBP β gene that has direct implication for acute phase response in liver cells.The C/EBP β form requires phosphorylation for its DNA binding ability, and increase binding of C/EBP β isoforms during acute-phase reaction occurs through its upregulation and structural modification.