mouse monoclonal IgG1; OSCP Antibody (A-8) is an IgG1 κ mouse monoclonal OSCP antibody (also designated OSCP antibody) that detects the OSCP protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. OSCP Antibody (A-8) is available as both the non-conjugated anti-OSCP antibody form, as well as multiple conjugated forms of anti-OSCP antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Oligomycin-sensitivity conferring protein (OSCP), also designated ATP5O, is the O subunit of ATP synthase which localizes to the mitochondria and catalyzes ATP synthesis. Mitochondrial ATP synthases (ATPases) transduce the energy contained in membrane electrochemical proton gradients into the energy required for synthesis of high-energy phosphate bonds. ATPases contain two linked complexes: F1, the hydrophilic catalytic core; and F0, the membrane-embedded protein channel. F1 consists of three α chains and three β chains, which are weakly homologous, as well as one γ chain, one δ chain and one e chain. F0 consists of three subunits: a, b and c. The e chain of F1 contains 50 amino acids and is the smallest of the five ATPase F1 chains.