mouse monoclonal IgG2b; L3MBTL2 Antibody (F-3) is an IgG2b κ mouse monoclonal L3MBTL2 antibody (also designated L3MBTL2 antibody) that detects the L3MBTL2 protein of mouse, rat and human origin by WB, IP, IF and ELISA. L3MBTL2 Antibody (F-3) is available as both the non-conjugated anti-L3MBTL2 antibody form, as well as multiple conjugated forms of anti-L3MBTL2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Polycomb group (PcG) proteins are important for maintaining the transcriptionally repressed state of target genes and are thought to function via chromatin modification. L3MBTL2 (Lethal(3)malignant brain tumor-like 2 protein), also known as L3MBT or H-l(3)mbt-l, is a 705 amino acid member of the PcG family. Localized to the nucleus, L3MBTL2 associates with chromatin-remodeling complexes and helps inhibit the expression of proteins that trigger the cell to enter mitosis. During the G0 phase of the cell cycle, L3MBTL2 is part of a complex that contains other proteins (such as HP1γ, E2F-6 and Max) that participate in transcriptional repression. L3MBTL2 contains one FCS-type zinc finger and four MBT repeats and is expressed as three isoforms due to alternative splicing events.