Oligonucleotide therapeutics have emerged as a promising novel class of drugs to treat a wide range of diseases. The development of these therapeutics relies on the proper use of chemical building blocks called phosphoramidites to generate high‑quality oligonucleotides. This webinar discusses techniques for phosphoramidite synthesis, selection, and evaluation for the development of oligonucleotide drugs.

Learning Objectives: 

1. Identify phosphoramidites for oligonucleotide therapeutic development and manufacturing.

2. Review phosphoramidite impurities and their potential impacts on oligonucleotide therapeutics.