De novo gene synthesis and protein expression are established technologies that can give access to nearly any target DNA or protein sequence, allowing for engineering of biologics. In this presentation we demonstrate how considering more than codon usage in gene optimization can boost protein expression. Advanced mammalian expression systems can further enhance antibody yields by getting more product from the same culture volumes. Customer examples demonstrate the benefits of a continuous workflow, from gene to protein, to accelerate discovery and early development.

Learning Objectives:

1. Explain how Enhancing Protein Expression: optimize gene synthesis techniques beyond codon usage can significantly improve protein expression rates, facilitating the engineering of biologics.

2. Summarize how Maximizing Antibody Yields: utilize advanced mammalian expression systems can increase antibody yields, extracting more product from identical culture volumes to accelerate discovery and early-stage development processes.